MOLECULAR IMMUNOBIOLOGY OF MACROPHAGES - RECENT PROGRESS

被引：95
|
作者：
GORDON, S [1 ]
CLARKE, S [1 ]
GREAVES, D [1 ]
DOYLE, A [1 ]
机构：
[1] QUEENSLAND INST MED RES, HERSTON, QLD 4006, AUSTRALIA
来源：
CURRENT OPINION IN IMMUNOLOGY | 1995年 / 7卷 / 01期
关键词：
D O I：
10.1016/0952-7915(95)80025-5
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Macrophage molecules involved in adhesion, signalling, secretion and interactions with pathogens and T-helper lymphocytes have been cloned and defined using monoclonal antibodies and genetic disruption. Studies of the regulation of macrophage differentiation and activation by cytokines have yielded insights into the heterogeneity of their functions in natural and acquired immunity, including immunity to infections by mycobacteria and HIV.
引用
收藏
页码：24 / 33
页数：10
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