Prolonged febrile illness due to CTX-M-15 extended-spectrum beta-lactamase-producing Klebsiella pneumoniae infection in Nigeria

被引：4
|
作者：
Aboderin, Oladipo A. [1 ,2 ]
Adefehinti, Olufemi [3 ]
Odetoyin, Babatunde W. [1 ]
Olotu, Amadin A. [2 ]
Okeke, Iruka N. [4 ]
Adeodu, Olugbenga O. [3 ,5 ]
机构：
[1] Obafemi Awolowo Univ, Dept Med Microbiol & Parasitol, Ife, Nigeria
[2] Obafemi Awolowo Univ Teaching Hosp Complex, Dept Med Microbiol & Parasitol, Ife, Nigeria
[3] Obafemi Awolowo Univ Teaching Hosp Complex, Dept Paediat, Ife, Nigeria
[4] Haverford Coll, Dept Biol, Haverford, PA 19041 USA
[5] Obafemi Awolowo Univ, Dept Paediat & Child Hlth, Ife, Nigeria
来源：
AFRICAN JOURNAL OF LABORATORY MEDICINE | 2012年 / 1卷 / 01期
关键词：
D O I：
10.4102/ajlm.v1i1.16
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
We report on an 8-year-old patient with septicaemia unresponsive to therapy for five weeks. Undetected, extended-spectrum beta-lactamase (ESBL) production by the infecting Klebsiella strain was regarded as responsible for treatment failure. Intravenously administered imipenem during the sixth week led to sustained resolution of fever. Resource-limited hospitals can incur prohibitive costs from ESBL-producer infections because of diagnostic limitations and consequent treatment failure involving prolonged supportive therapy.
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页数：4
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