ACCUMULATION AND PERSISTENCE OF DNA ADDUCTS IN RESPIRATORY TISSUE OF RATS FOLLOWING MULTIPLE ADMINISTRATIONS OF THE TOBACCO SPECIFIC CARCINOGEN 4-(N-METHYL-N-NITROSAMINO)-1-(3-PYRIDYL)-1-BUTANONE

被引：0
|
作者：
BELINSKY, SA [1 ]
WHITE, CM [1 ]
BOUCHERON, JA [1 ]
RICHARDSON, FC [1 ]
SWENBERG, JA [1 ]
ANDERSON, M [1 ]
机构：
[1] CHEM IND INST TOXICOL,DEPT BIOCHEM TOXICOL & PATHOBIOL,RES TRIANGLE PK,NC 27709
来源：
CANCER RESEARCH | 1986年 / 46卷 / 03期
关键词：
D O I：
暂无
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
引用
收藏
页码：1280 / 1284
页数：5
相关论文
共 50 条
  • [31] TISSUE DISTRIBUTION OF THE TOBACCO-SPECIFIC CARCINOGEN 4-(METHYLNITROSAMINO)-1-(3-PYRIDYL)-1-BUTANONE AND ITS METABOLITES IN F344 RATS
    CASTONGUAY, A
    TJALVE, H
    HECHT, SS
    CANCER RESEARCH, 1983, 43 (02) : 630 - 638
  • [32] Extensive metabolic activation of the tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in smokers
    Stepanov, Irina
    Upadhyaya, Pramod
    Carmella, Steven G.
    Feuer, Rachel
    Jensen, Joni
    Hatsukarni, Dorothy K.
    Hecht, Stephen S.
    CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION, 2008, 17 (07) : 1764 - 1773
  • [33] ACTIVATION OF THE K-RAS PROTOONCOGENE IN LUNG-TUMORS FROM MICE TREATED WITH 4-(N-METHYL-N-NITROSAMINO)-1-(3-PYRIDYL)-1-BUTANONE (NNK) OR NITROSODIMETHYLAMINE (NDMA)
    BELINSKY, SA
    DEVEREUX, TR
    STONER, GD
    ANDERSON, MW
    PROCEEDINGS OF THE AMERICAN ASSOCIATION FOR CANCER RESEARCH, 1988, 29 : 139 - 139
  • [34] EVIDENCE FOR 4-(3-PYRIDYL)-4-OXOBUTYLATION OF DNA IN F344 RATS TREATED WITH THE TOBACCO-SPECIFIC NITROSAMINES 4-(METHYLNITROSAMINO)-1-(3-PYRIDYL)-1-BUTANONE AND N'-NITROSONORNICOTINE
    HECHT, SS
    SPRATT, TE
    TRUSHIN, N
    CARCINOGENESIS, 1988, 9 (01) : 161 - 165
  • [35] Racial differences in exposure and glucuronidation of the tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)
    Muscat, JE
    Djordjevic, MV
    Colosimo, S
    Stellman, SD
    Richie, JP
    CANCER, 2005, 103 (07) : 1420 - 1426
  • [36] Kava Effects on the Metabolism of Tobacco-Specific Carcinogen 4-(Methylnitrosamino)-1-(3-Pyridyl)-1-Butanone (NNK) in Humans
    Oostra, Drew
    Fujioka, Naomi
    Xing, Chengguo
    Narayanapillai, Sreekanth
    Paladino, Jordan
    Alves, Hannah
    JOURNAL OF THORACIC ONCOLOGY, 2017, 12 (01) : S455 - S455
  • [37] Analysis of phosphate adducts in hepatic and pulmonary DNA of rats treated with 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone
    Ma, Bin
    Villalta, Peter
    Zarth, Adam
    Kotandeniya, Delshanee
    Upadhyaya, Pramod
    Stepanov, Irina
    Hecht, Stephen
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2015, 250
  • [38] INVESTIGATIONS OF METABOLIC PRECURSORS TO HEMOGLOBIN AND DNA ADDUCTS OF 4-(METHYLNITROSAMINO)-1-(3-PYRIDYL)-1-BUTANONE
    PETERSON, LA
    CARMELLA, SG
    HECHT, SS
    CARCINOGENESIS, 1990, 11 (08) : 1329 - 1333
  • [39] An update on the formation in tobacco, toxicity and carcinogenicity of N′-nitrosonornicotine and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone
    Peterson, Lisa A.
    Stanfill, Stephen B.
    Hecht, Stephen S.
    CARCINOGENESIS, 2024, 45 (05) : 275 - 287
  • [40] Pyridylhydroxybutyl DNA phosphate adduct formation in rats treated chronically with the tobacco-specific lung carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone
    Ma, Bin
    Zarth, Adam
    Villalta, Peter
    Upadhyaya, Pramod
    Stepanov, Irina
    Hecht, Stephen
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2016, 252
12345