GRANULOCYTE COLONY STIMULATING FACTOR IN THE MANAGEMENT OF CHRONIC NEUTROPENIA

被引：5
|
作者：
MARLTON, PV [1 ]
WRIGHT, SJ [1 ]
TAYLOR, KM [1 ]
机构：
[1] MATER MISERICORDIAE HOSP,DEPT HAEMATOL,BRISBANE,QLD 4101,AUSTRALIA
来源：
MEDICAL JOURNAL OF AUSTRALIA | 1992年 / 156卷 / 10期
关键词：
D O I：
10.5694/j.1326-5377.1992.tb121518.x
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Objective: To report two cases of chronic neutropenic states successfully treated with granulocyte colony stimulating factor (G-CSF). Clinical features: A 23-year-old man with severe congenital cyclic neutropenia causing lifelong recurrent infections and consequent debilitation presented with intractable infected leg ulcers. A 56-year-old man with acquired idiopathic neutropenia presented with severe perianal infection and sepsis. Intervention and outcome: Both patients were successfully treated with recombinant G-CSF. Conclusion: G-CSF is an agent with major clinical potential for the therapy of primary neutropenic states.
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页码：729 / 731
页数：3
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