EFFECTS OF INTRACAROTID INFUSION OF NEUROPEPTIDE-Y ON CEREBRAL BLOOD-FLOW IN RATS

被引：2
|
作者：
OKAZAKI, S [1 ]
SAKO, K [1 ]
YONEMASU, Y [1 ]
机构：
[1] ASAHIKAWA MED COLL,DEPT NEUROSURG,4-5 NISHIKAGURA,ASAHIKAWA 078,JAPAN
来源：
BRAIN RESEARCH | 1992年 / 575卷 / 02期
关键词：
NEUROPEPTIDE-Y; CEREBRAL BLOOD FLOW; AUTORADIOGRAPHY; RAT; INTRACAROTID INFUSION; C-14]IODOANTIPYRINE;
D O I：
10.1016/0006-8993(92)90103-G
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
Neuropeptide Y (NPY) was continuously administered to Wistar rats intracarotidly via the external carotid artery and local cerebral blood flow (LCBF) was measured by a quantitative autoradiography using [C-14]iodoantipyrine. A remarkable reduction in LCBF was observed in the NPY infused hemisphere. This depression was irregular and was particularly evident in the hippocampus, selective thalamic nuclei and the cerebral cortex.
引用
收藏
页码：347 / 350
页数：4
相关论文
共 50 条
  • [21] EFFECTS OF NEUROPEPTIDE-Y AND NORADRENALINE ON UTERINE ARTERY BLOOD-PRESSURE AND BLOOD-FLOW VELOCITY IN THE PREGNANT GUINEA-PIG
    FRIED, G
    THORESEN, M
    [J]. REGULATORY PEPTIDES, 1990, 28 (01) : 1 - 9
  • [22] Effect of intracarotid bradykinin infusion on cerebral blood flow in dogs
    Muraishi, M
    Sayama, T
    Matsukado, K
    Inamura, T
    Ikezaki, K
    Morioka, T
    Fukui, M
    [J]. NEUROLOGICAL RESEARCH, 1999, 21 (08) : 791 - 795
  • [23] NEUROPEPTIDE-Y AND DIFFERENTIAL SYMPATHETIC CONTROL OF SPLENIC BLOOD-FLOW AND CAPACITANCE FUNCTION IN THE PIG AND DOG
    MODIN, A
    PERNOW, J
    LUNDBERG, JM
    [J]. ACTA PHYSIOLOGICA SCANDINAVICA, 1993, 147 (01): : 15 - 25
  • [24] ACTIONS OF NORADRENALINE AND NEUROPEPTIDE-Y ON GASTRIC-MUCOSAL BLOOD-FLOW AND INTEGRITY IN THE ANESTHETIZED RAT
    TEPPERMAN, BL
    WHITTLE, BJR
    [J]. JOURNAL OF PHYSIOLOGY-LONDON, 1990, 426 : P87 - P87
  • [25] RELEASE AND VASOCONSTRICTOR EFFECTS OF NEUROPEPTIDE-Y IN RELATION TO NON-ADRENERGIC SYMPATHETIC CONTROL OF RENAL BLOOD-FLOW IN THE PIG
    PERNOW, J
    LUNDBERG, JM
    [J]. ACTA PHYSIOLOGICA SCANDINAVICA, 1989, 136 (04): : 507 - 517
  • [26] CARDIOVASCULAR EFFECTS OF INTRACEREBRAL INJECTION OF NEUROPEPTIDE-Y IN RATS
    YANG, SN
    YANG, W
    TANG, YH
    WANG, S
    [J]. ACTA PHARMACOLOGICA SINICA, 1992, 13 (02): : 116 - 118
  • [27] INCREASING DOSES OF INTRACAROTID AIR AND CEREBRAL BLOOD-FLOW IN RABBITS
    HELPS, SC
    MEYERWITTING, M
    REILLY, PL
    GORMAN, DF
    [J]. STROKE, 1990, 21 (09) : 1340 - 1345
  • [28] INTRACAROTID INFUSION OF A NITRIC-OXIDE DONATING COMPOUND IN PRIMATES INCREASES CEREBRAL BLOOD-FLOW AND RESOLVES CEREBRAL VASOSPASM
    BOOCK, RJ
    PLUTA, RM
    AFSHAR, KB
    OLDFIELD, EH
    [J]. STROKE, 1994, 25 (01) : 265 - 265
  • [29] NEUROPEPTIDE-Y AND THE CEREBRAL-CIRCULATION
    TUOR, UI
    KELLY, PAT
    EDVINSSON, L
    MCCULLOCH, J
    [J]. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM, 1990, 10 (05): : 591 - 601
  • [30] ROLE OF PLASMA NEUROPEPTIDE-Y CONCENTRATIONS IN THE HYPERRESPONSIVENESS OF BLOOD-PRESSURE IN SPONTANEOUSLY HYPERTENSIVE RATS TO EXOGENOUS NEUROPEPTIDE-Y
    MILLER, DW
    TESSEL, RE
    [J]. FASEB JOURNAL, 1988, 2 (05): : A1525 - A1525
12345