EFFECTS OF INTRACAROTID INFUSION OF NEUROPEPTIDE-Y ON CEREBRAL BLOOD-FLOW IN RATS

被引：2
|
作者：
OKAZAKI, S [1 ]
SAKO, K [1 ]
YONEMASU, Y [1 ]
机构：
[1] ASAHIKAWA MED COLL,DEPT NEUROSURG,4-5 NISHIKAGURA,ASAHIKAWA 078,JAPAN
来源：
BRAIN RESEARCH | 1992年 / 575卷 / 02期
关键词：
NEUROPEPTIDE-Y; CEREBRAL BLOOD FLOW; AUTORADIOGRAPHY; RAT; INTRACAROTID INFUSION; C-14]IODOANTIPYRINE;
D O I：
10.1016/0006-8993(92)90103-G
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
Neuropeptide Y (NPY) was continuously administered to Wistar rats intracarotidly via the external carotid artery and local cerebral blood flow (LCBF) was measured by a quantitative autoradiography using [C-14]iodoantipyrine. A remarkable reduction in LCBF was observed in the NPY infused hemisphere. This depression was irregular and was particularly evident in the hippocampus, selective thalamic nuclei and the cerebral cortex.
引用
收藏
页码：347 / 350
页数：4
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