HIGH-CAPACITY FOR PULMONARY 1ST-PASS ELIMINATION OF PROPRANOLOL IN RATS

被引：15
|
作者：
IWAMOTO, K [1 ]
WATANABE, J [1 ]
AOYAMA, Y [1 ]
机构：
[1] NAGOYA CITY UNIV,FAC PHARMACEUT SCI,DEPT BIOPHARMACEUT,NAGOYA,AICHI 467,JAPAN
来源：
JOURNAL OF PHARMACY AND PHARMACOLOGY | 1987年 / 39卷 / 12期
关键词：
D O I：
10.1111/j.2042-7158.1987.tb03162.x
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
引用
收藏
页码：1049 / 1051
页数：3
相关论文
共 50 条
  • [41] PHARMACOKINETIC STUDY OF 4-METHYLUMBELLIFERONE IN RATS - INFLUENCE OF DOSE ON ITS 1ST-PASS HEPATIC ELIMINATION
    MORITA, K
    SUGIYAMA, Y
    HANANO, M
    JOURNAL OF PHARMACOBIO-DYNAMICS, 1986, 9 (02): : 117 - 124
  • [42] METABOLIC 1ST-PASS EFFECTS
    PANG, KS
    JOURNAL OF CLINICAL PHARMACOLOGY, 1986, 26 (08): : 580 - 582
  • [43] 1ST-PASS EFFECT OF DAURICINE
    GUI, YT
    DU, ZH
    ZENG, FD
    HU, CJ
    ACTA PHARMACOLOGICA SINICA, 1993, 14 (02): : 173 - 175
  • [44] POTENTIAL PITFALLS IN THE CONVENTIONAL PHARMACOKINETIC STUDIES - EFFECTS OF THE INITIAL MIXING OF DRUG IN BLOOD AND THE PULMONARY 1ST-PASS ELIMINATION
    CHIOU, WL
    JOURNAL OF PHARMACOKINETICS AND BIOPHARMACEUTICS, 1979, 7 (05): : 527 - 536
  • [45] PHARMACOKINETIC STUDIES OF PROPOXYPHENE .6. ACUTE EFFECT OF ETHANOL ON HEPATIC 1ST-PASS ELIMINATION OF PROPOXYPHENE IN RATS
    OGUMA, T
    LEVY, G
    JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 1981, 219 (01): : 7 - 13
  • [46] PREFERENTIAL REDUCTION OF 1ST-PASS ELIMINATION BY ETHANOL - MODEL EXPERIMENTS WITH CLOMETHIAZOLE IN THE RABBIT
    ZYSSET, T
    BIRCHER, J
    JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 1981, 217 (01): : 198 - 203
  • [47] RELATIONSHIP BETWEEN PROPERTY OF ENZYMES INVOLVED IN PROPRANOLOL METABOLISM AND NONLINEAR 1ST-PASS METABOLISM
    SUZUKI, K
    CHIBA, M
    FUJITA, S
    SUZUKI, T
    JOURNAL OF PHARMACEUTICAL SCIENCES, 1987, 76 (11) : S97 - S97
  • [48] REDUCTION OF 1ST-PASS METABOLISM OF PROPRANOLOL AFTER ORAL-ADMINISTRATION OF ESTER PRODRUGS
    ANDERSON, BD
    CHU, WW
    GALINSKY, RE
    INTERNATIONAL JOURNAL OF PHARMACEUTICS, 1988, 43 (03) : 261 - 265
  • [49] THE EFFECT OF GENERAL-ANESTHESIA ON 1ST-PASS PROPRANOLOL UPTAKE IN DOG LUNGS INVIVO
    PANG, JA
    BLACKBURN, JP
    BUTLAND, RJA
    WILLIAMS, TR
    GEDDES, DM
    BRITISH JOURNAL OF PHARMACOLOGY, 1980, 70 (01) : P173 - P173
  • [50] DISPOSITION OF HEXOBARBITAL IN THE RAT - ESTIMATION OF 1ST-PASS ELIMINATION AND INFLUENCE OF ETHER ANESTHESIA
    VERMEULEN, NPE
    DANHOF, M
    SETIAWAN, I
    BREIMER, DD
    JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 1983, 226 (01): : 201 - 205
12345