THE EFFECTS OF CISPLATIN ON MURINE METAPHASE-II OOCYTES

被引：24

作者：

HIGDON, RE ^{[1
]}

MARCHETTI, F ^{[1
]}

MAILHES, JB ^{[1
]}

PHILLIPS, GL ^{[1
]}

机构：

[1] LOUISIANA STATE UNIV,MED CTR,DIV GYNECOL ONCOL,SHREVEPORT,LA 71130

来源：

GYNECOLOGIC ONCOLOGY | 1992年 / 47卷 / 03期

关键词：

D O I：

10.1016/0090-8258(92)90138-9

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

This study was undertaken to determine if cisplatin can induce aneuploidy in murine oocytes treated prior to ovulation. Control animals were injected with intraperitoneal (ip) saline and the treatment animals were divided into three different dose schedules for ip cisplatin. After ovulation induction, the oocytes were processed for cytogenetic analysis and the chromosomes were counted. There were significantly less oocytes ovulated in the treatment groups when compared to control animals. There was a significant increase in hypohaploid cells counted in the 7.5 mg/kg treatment group, but the percentages of hyperhaploid and polyploid cells were not increased in the treatment groups. The cytogenetic effects of cisplatin in vivo and in vitro are reviewed. © 1992.

引用

页码：348 / 352

页数：5

共 50 条

[41] ULTRASTRUCTURE OF CELL-FUSION AND PREMATURE CHROMOSOME CONDENSATION (PCC) OF THYMOCYTE NUCLEI IN METAPHASE-II MOUSE OOCYTES
SZOLLOSI, D
CZOLOWSKA, R
SOLTYNSKA, MS
TARKOWSKI, AK
BIOLOGY OF THE CELL, 1986, 56 (03) : 239 - 249
[42] ROLE OF MELATONIN IN PREVENTING HYPOCHLOROUS ACID INDUCED ALTERATIONS IN MICROTUBULE AND CHROMOSOMAL STRUCTURE IN METAPHASE-II MOUSE OOCYTES IN VITRO
Banerjee, J.
Maitra, D.
Shaeib, F.
Saed, G. M.
Diamond, M. P.
Abu-Soud, H.
FERTILITY AND STERILITY, 2011, 96 (03) : S239 - S239
[43] Altered microfilament dynamics contribute to the formation of diploid metaphase spindles in porcine oocytes which fail to reach the metaphase-II stage during in vitro maturation
Somfai, Tamas
Dang-Nguyen, Thanh Quang
Kikuchi, Kazuhiro
ANIMAL SCIENCE JOURNAL, 2022, 93 (01)
[44] Effects of hydroxyapatite nanoparticles on the vitrification of bovine metaphase II oocytes
Liu, Yi-Heng
Wang, Xiao-Jing
Liu, Jia-Qi
Zhao, Shi-Yu
Xu, Zhi-Qian
Li, Xiao-Xia
Li, Ying-Hua
Yu, Xue-Li
ANIMAL PRODUCTION SCIENCE, 2023, 63 (13) : 1288 - 1295
[45] THE METAPHASE-II ARREST IN MOUSE OOCYTES IS CONTROLLED THROUGH MICROTUBULE-DEPENDENT DESTRUCTION OF CYCLIN-B IN THE PRESENCE OF CSF
KUBIAK, JZ
WEBER, M
DEPENNART, H
WINSTON, NJ
MARO, B
EMBO JOURNAL, 1993, 12 (10): : 3773 - 3778
[46] Endometriosis shows no impact on the euploid blastocyst rate per cohort of inseminated metaphase-II oocytes: A case-control study
Vaiarelli, Alberto
Venturella, Roberta
Cimadomo, Danilo
Conforti, Alessandro
Pedri, Sara
Bitonti, Giovanna
Iussig, Benedetta
Gentile, Cinzia
Alviggi, Erminia
Santopaolo, Serena
Zullo, Fulvio
Rienzi, Laura
Ubaldi, Filippo Maria
EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY, 2021, 256 : 205 - 210
[47] Prolactin and growth hormone affect metaphase-II chromosomes in aging oocytes via cumulus cells using similar signaling pathways
Lebedeva, Irina Y.
Singina, Galina N.
Lopukhov, Alexander V.
Shedova, Ekaterina N.
Zinovieva, Natalia A.
FRONTIERS IN GENETICS, 2015, 6
[48] Protective effect of coincubating oocytes with antioxidants against oxidative stress induced alterations in metaphase-II mouse oocyte spindle.
Banerjee, J.
Sharma, R. K.
Choi, W.
Agarwal, A.
Goldberg, J. M.
Falcone, T.
FERTILITY AND STERILITY, 2006, 86 : S447 - S448
[49] CYTOSKELETAL ORGANIZATION OF RAT OOCYTES DURING METAPHASE-II ARREST AND FOLLOWING ABORTIVE ACTIVATION - A STUDY BY CONFOCAL LASER SCANNING MICROSCOPY
ZERNICKAGOETZ, M
KUBIAK, JZ
ANTONY, C
MARO, B
MOLECULAR REPRODUCTION AND DEVELOPMENT, 1993, 35 (02) : 165 - 175
[50] MATURATION OF HUMAN CUMULUS-FREE GERMINAL VESICLE-STAGE OOCYTES TO METAPHASE-II BY COCULTURE WITH MONOLAYER VERO CELLS
JANSSENSWILLEN, C
NAGY, ZP
VANSTEIRTEGHEM, A
HUMAN REPRODUCTION, 1995, 10 (02) : 375 - 378

← 1 2 3 4 5 →