AN EFFICIENT SYNTHESIS OF ENANTIOMERICALLY PURE TRANS-2-PHENYLCYCLOHEXANOL

被引:49
|
作者
KING, SB [1 ]
SHARPLESS, KB [1 ]
机构
[1] Scripps Res Inst, DEPT CHEM, LA JOLLA, CA 92037 USA
关键词
D O I
10.1016/S0040-4039(00)77259-5
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Both enantiomers of trans-2-phenylcyclohexanol (3), Whitesell's auxiliary, have been prepared in a simple two step sequence featuring a catalytic asymmetric dihydroxylation followed by stereoselective hydrogenolysis
引用
收藏
页码:5611 / 5612
页数:2
相关论文
共 50 条
  • [41] Efficient synthesis of enantiomerically pure C-2-symmetric diols via the allylboration of appropriate dialdehydes
    Ramachandran, PV
    Chen, GM
    Brown, HC
    TETRAHEDRON LETTERS, 1997, 38 (14) : 2417 - 2420
  • [42] Synthesis of allylamines in enantiomerically pure form
    Concellón, JM
    Baragaña, B
    Riego, E
    TETRAHEDRON LETTERS, 2000, 41 (22) : 4361 - 4362
  • [43] Synthesis of enantiomerically pure isotopomers of 2-phenylpropionic acids
    Chavda, Sameer
    Coumbarides, Gregory S.
    Dingjan, Marco
    Eames, Jason
    Flinn, Anthony
    Ghilagaber, Stephanos
    Northen, Julian
    Yohannes, Yonas
    CHIRALITY, 2007, 19 (05) : 366 - 373
  • [44] AN EFFICIENT SYNTHESIS OF ENANTIOMERICALLY PURE (R)-(2-BENZYLOXYETHYL)OXIRANE FROM (S)-ASPARTIC ACID
    FRICK, JA
    KLASSEN, JB
    BATHE, A
    ABRAMSON, JM
    RAPOPORT, H
    SYNTHESIS-STUTTGART, 1992, (07): : 621 - 623
  • [45] Asymmetric Hydroformylation of an Enantiomerically Pure Bicyclic Lactam: Efficient Synthesis of Functionalised Cyclopentylamines
    Noonan, Gary M.
    Cobley, Christopher J.
    Lebl, Tomas
    Clarke, Matthew L.
    CHEMISTRY-A EUROPEAN JOURNAL, 2010, 16 (43) : 12788 - 12791
  • [46] A new and extremely efficient, general strategy for the synthesis of enantiomerically pure iridoid aglycones
    Marco-Contelles, J
    Ruiz, J
    TETRAHEDRON LETTERS, 1998, 39 (35) : 6393 - 6394
  • [47] Synthesis of Enantiomerically Pure 4-Hydroxy-2-cyclopentenones
    Kumaraguru, Thenkrishnan
    Babita, Panuganti
    Sheelu, Gurrala
    Lavanya, Kuna
    Fadnavis, Nitin W.
    ORGANIC PROCESS RESEARCH & DEVELOPMENT, 2013, 17 (12) : 1526 - 1530
  • [48] A refined synthesis of enantiomerically pure 2-aminocyclobutanecarboxylic acids
    Valérie Declerck
    David J. Aitken
    Amino Acids, 2011, 41 : 587 - 595
  • [49] Total Synthesis of Enantiomerically Pure (-)-Balanol
    Chimia Chemie Rep, 11 (530):
  • [50] Synthesis of enantiomerically pure δ-benzylproline derivatives
    Rodriguez, Isabel
    Isabel Calaza, M.
    Jimenez, Ana I.
    Cativiela, Carlos
    NEW JOURNAL OF CHEMISTRY, 2015, 39 (05) : 3310 - 3318