In the United States more than 1.5 million pulmonary artery catheters (PACs) are inserted each year. Of these, approximately 55% are placed in high-risk surgical and trauma patients. Most clinicians believe that PAC use is beneficial in guiding therapy and may improve outcome. Despite these beliefs and hundreds of published articles related to PACs, appropriate use and impact on outcome remain unclear. A review of the current literature reveals conflicting data and significant flaws in most study designs. Inadequate sample size, lack of randomization, lack of standardization of therapies to PAC data, and deficiencies in user knowledge all significantly limit interpretation of clinical trials. Despite these deficiencies and the need for better-designed investigations, it is the opinion of the authors that access to hemodynamic data provided by the PAC, coupled with accurate interpretation of the data, may lead to reduced perioperative morbidity and mortality.
机构:
University Health Network, University of Toronto, Department of Medicine, Division of Respirology, Interdepartmental Division of Critical Care Medicine, ONUniversity Health Network, University of Toronto, Department of Medicine, Division of Respirology, Interdepartmental Division of Critical Care Medicine, ON
机构:
Mt Sinai Hosp, Zena & Michael A Weiner Cardiovasc Inst, New York, NY 10029 USA
Icahn Sch Med Mt Sinai, New York, NY 10029 USAMt Sinai Hosp, Zena & Michael A Weiner Cardiovasc Inst, New York, NY 10029 USA
Gidwani, Umesh K.
Mohanty, Bibhu
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机构:
Mt Sinai Hosp, Zena & Michael A Weiner Cardiovasc Inst, New York, NY 10029 USAMt Sinai Hosp, Zena & Michael A Weiner Cardiovasc Inst, New York, NY 10029 USA
Mohanty, Bibhu
Chatterjee, Kanu
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机构:
Univ Iowa, Carver Coll Med, Iowa City, IA 52242 USA
Univ Calif San Francisco, San Francisco, CA 94143 USAMt Sinai Hosp, Zena & Michael A Weiner Cardiovasc Inst, New York, NY 10029 USA