SYNTHESIS OF 2,6-DISUBSTITUTED AND 2,3,6-TRISUBSTITUTED ANILINES

被引：9
|
作者：
PEWS, RG
HUNTER, JE
WEHMEYER, RM
机构：
[1] Central Research Laboratory, The Dow Chemical Company, Midland
来源：
TETRAHEDRON | 1993年 / 49卷 / 22期
关键词：
D O I：
10.1016/S0040-4020(01)80400-2
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A number of 2,6-disubstituted and 2,3,6-trisubstituted anilines have been prepared via the selective para dehalogenation of the corresponding anilines. Modification of the substituents on the amino nitrogen demonstrates that the selectivity is derived from steric rather than electronic effects. The effects of the choice of formate hydrogen donor, Pd catalyst, solvent, and temperature upon the efficiency and selectivity of the dehalogenation are discussed.
引用
收藏
页码：4809 / 4820
页数：12
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