A RANDOMIZED PROSPECTIVE CONTROLLED-STUDY OF CIPROFLOXACIN WITH METRONIDAZOLE VERSUS AMOXICILLIN CLAVULANIC ACID WITH METRONIDAZOLE IN THE TREATMENT OF INTRAABDOMINAL INFECTION

被引：20
|
作者：
YOSHIOKA, K
YOUNGS, DJ
KEIGHLEY, MRB
机构：
[1] KANSAI MED UNIV,DEPT SURG,MORIGUCHI,OSAKA 570,JAPAN
[2] GEN HOSP,DEPT MICROBIOL,BIRMINGHAM B4 6NH,W MIDLANDS,ENGLAND
[3] GEN HOSP,DEPT SURG,BIRMINGHAM B4 6NH,W MIDLANDS,ENGLAND
来源：
INFECTION | 1991年 / 19卷 / 01期
关键词：
D O I：
10.1007/BF01643754
中图分类号：
R51 [传染病];
学科分类号：
100401 ;
摘要：
A prospective randomised study was undertaken in 80 patients to assess the combined regimen of ciprofloxacin with metronidazole against amoxicillin/clavulanic acid with metronidazole as treatment for established intra-abdominal infection. Treatment was for five days. Seventy-eight patients were clinically evaluable (38 patients on ciprofloxacin with metronidazole and 40 patients on amoxicillin/clavulanic acid with metronidazole). The overall clinical success rate in the treatment of intra-abdominal infections was 96% for the ciprofloxacin with metronidazole group, and 90% for the amoxicillin/clavulanic acid with metronidazole group. Over half of all patients were able to change from intravenous to oral antibiotic administration within the study period. One patient receiving ciprofloxacin with metronidazole developed pruritus near the injection site.
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页码：25 / 29
页数：5
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