2-DIBENZYLAMINOBUTANE-1,4-DIOL - A VERSATILE INTERMEDIATE FOR A CHIROSPECIFIC BETA-AMINO ACID SYNTHESIS

被引：23
|
作者：
GMEINER, P
ORECHER, F
THOMAS, C
WEBER, K
机构：
[1] Pharmazeutisches Institut der Universität Bonn, D-53121 Bonn
来源：
TETRAHEDRON LETTERS | 1995年 / 36卷 / 03期
关键词：
D O I：
10.1016/0040-4039(94)02307-W
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Starting from the chiral building block 1, which is readily available from natural aspartic acid, a concise and versatile synthesis of optically active beta-amino acids including beta-proline derivatives is reported. Regioselective transformations of the 1,4-bis-electrophile 2 are facilitated by an anchimeric participation.
引用
收藏
页码：381 / 382
页数：2
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