WHY USE BUBBLE-COLUMN BIOREACTORS

被引：20
|
作者：
MERCHUK, JC
BENZVI, S
NIRANJAN, K
机构：
[1] BEN GURION UNIV NEGEV,PROGRAM BIOTECHNOL,IL-84105 BEER SHEVA,ISRAEL
[2] UNIV READING,DEPT FOOD SCI & TECHNOL,BIOCHEM ENGN GRP,READING RG6 2AP,BERKS,ENGLAND
来源：
TRENDS IN BIOTECHNOLOGY | 1994年 / 12卷 / 12期
关键词：
D O I：
10.1016/0167-7799(94)90058-2
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
Among the plethora of bioreactors available for aerobic culture, bubble columns, which are composed of a cylindrical vessel fitted with a gas sparger, are gaining in use. The simple construction of bubble-column reactors makes them easy to maintain. In addition, it is possible to control the degree of shear, uniformly within the reactor, which is critical to the growth of plant and animal cells in particular. This article reviews in detail the hydrodynamic, heat and mass-transfer characteristics of bubble-column bioreactors-parameters that are important for industrial scale-up.
引用
收藏
页码：501 / 511
页数：11
相关论文
共 50 条
  • [41] Ozonation of aqueous dyes and dyehouse effluent in a bubble-column reactor
    Hassan, MM
    Hawkyard, CJ
    JOURNAL OF ENVIRONMENTAL SCIENCE AND HEALTH PART A-TOXIC/HAZARDOUS SUBSTANCES & ENVIRONMENTAL ENGINEERING, 2002, 37 (08): : 1563 - 1579
  • [42] SIMULATION OF AN INDUSTRIAL BUBBLE-COLUMN REACTOR WITH EMPHASIS ON REAL FLOW
    HERTWIG, K
    SCHMIDT, R
    NAGEL, G
    INTERNATIONAL CHEMICAL ENGINEERING, 1978, 18 (04): : 582 - 585
  • [43] MEASURING PRINCIPLES FOR CHARACTERIZATION OF BUBBLE COLUMN BIOREACTORS
    LIPPERT, J
    ADLER, I
    MEYER, HD
    LUBBERT, A
    SCHUGERL, K
    CHEMIE INGENIEUR TECHNIK, 1981, 53 (12) : 967 - 967
  • [44] ELECTROCHEMICAL MASS-TRANSFER TO REGULAR PACKINGS IN A BUBBLE-COLUMN
    TASAT, AI
    CAVATORTA, ON
    BOHM, U
    JOURNAL OF APPLIED ELECTROCHEMISTRY, 1995, 25 (03) : 273 - 278
  • [45] FLOW CHARACTERISTICS OF BUBBLE-COLUMN WITH PACKED PERFORATED DRAFT TUBE
    BANDO, Y
    NISHIMURA, M
    WATANABE, Y
    SATO, A
    MIWA, M
    KURAISHI, M
    KAWASE, N
    IDOTA, A
    KAGAKU KOGAKU RONBUNSHU, 1993, 19 (03) : 489 - 495
  • [46] 2-BUBBLE CLASS MODEL FOR CHURN-TURBULENT BUBBLE-COLUMN REACTOR
    SHAH, YT
    JOSEPH, S
    SMITH, DN
    RUETHER, JA
    INDUSTRIAL & ENGINEERING CHEMISTRY PROCESS DESIGN AND DEVELOPMENT, 1985, 24 (04): : 1096 - 1104
  • [47] GAS HOLDUP AND BUBBLE FREQUENCY IN A BUBBLE-COLUMN REACTOR CONTAINING VISCOUS SACCHAROSE SOLUTIONS
    KUNCOVA, G
    ZAHRADNIK, J
    CHEMICAL ENGINEERING AND PROCESSING-PROCESS INTENSIFICATION, 1995, 34 (01) : 25 - 34
  • [48] FLOW VISUALIZATION OF HIGH-PRESSURE (21 MPA) BUBBLE-COLUMN - BUBBLE CHARACTERISTICS
    JIANG, P
    LIN, TJ
    LUO, X
    FAN, LS
    CHEMICAL ENGINEERING RESEARCH & DESIGN, 1995, 73 (A3): : 269 - 274
  • [49] Modeling and Simulation of Hydrodynamic Bubble-Liquid Turbulent Flows in Bubble-Column Reactors
    Li, Xiangli
    Li, Guohui
    CHEMICAL ENGINEERING & TECHNOLOGY, 2016, 39 (12) : 2380 - 2388
  • [50] CRITICAL GAS VELOCITY FOR COMPLETE SUSPENSION OF SOLID PARTICLES IN BUBBLE-COLUMN
    FURUMOTO, K
    IMURA, T
    NAKAO, K
    KAGAKU KOGAKU RONBUNSHU, 1995, 21 (01) : 196 - 203
12345