SF2487, A NEW POLYETHER ANTIBIOTIC PRODUCED BY ACTINOMADURA

被引：14

作者：

HATSU, M ^{[1
]}

SASAKI, T ^{[1
]}

MIYADOH, S ^{[1
]}

WATABE, H ^{[1
]}

TAKEUCHI, Y ^{[1
]}

KODAMA, Y ^{[1
]}

ORIKASA, Y ^{[1
]}

KAJII, K ^{[1
]}

SHOMURA, T ^{[1
]}

YAMAMOTO, H ^{[1
]}

SEZAKI, M ^{[1
]}

INOUYE, S ^{[1
]}

KONDO, S ^{[1
]}

机构：

[1] MEIJI SEIKA KAISHA LTD,PHARMACEUT RES CTR,MOROOKA CHO,KOHOKU KU,YOKOHAMA,KANAGAWA 222,JAPAN

来源：

JOURNAL OF ANTIBIOTICS | 1990年 / 43卷 / 03期

关键词：

D O I：

10.7164/antibiotics.43.259

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

A new antibiotic SF2487 has been isolated from the culture broth of Actinomadura sp. SF2487. The structure of antibiotic SF2487 was determined by spectroscopic analyses of the sodium salt and X-ray diffraction analysis of the silver salt. The antibiotic represents a new member of polyether group antibiotics known as the acyltetronic acid type 4. The antibiotic is weakly active against Gram-positive bacteria and exhibits antiviral activity against influenza virus in vitro. © 1990, JAPAN ANTIBIOTICS RESEARCH ASSOCIATION. All rights reserved.

引用

页码：259 / 266

页数：8

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