Pathogenetic mechanisms and treatment principles of chronic thromboembolic pulmonary hypertension

被引：0
|
作者：
Shostak, N. A. [1 ]
Klimenko, A. A. [1 ]
Demidova, N. A. [1 ]
Novikov, I. V. [1 ]
机构：
[1] Russian State Med Univ, Ostrovitjanova 1, Moscow 117997, Russia
来源：
RATIONAL PHARMACOTHERAPY IN CARDIOLOGY | 2011年 / 7卷 / 02期
关键词：
pulmonary hypertension; chronic thromboembolic pulmonary hypertension; thromboembolism of pulmonary artery; thromboendarterectomy; bosentan; prostacyclin analogues; phosphodiesterase-5; inhibitors;
D O I：
10.20996/1819-6446-2011-7-2-199-203
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Data about chronic thromboembolic pulmonary hypertension (CTPH) prevalence is presented. The main CTPH clinical manifestations are described. The possible reasons and pathogenetic mechanisms of CTPH development are discussed. Features of unfavorable disease prognosis are also presented. Indications, results, limitations for CTPH surgical treatment are shown. Data of the currently completed clinical studies on bosentan, prostacyclin analogues and phosphodiesterase-5 inhibitors usage in CTPH are presented.
引用
收藏
页码：199 / 203
页数：5
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