BIOCHEMICAL EVENTS IN THE DEVELOPMENT OF PARKINSONISM INDUCED BY 1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE

被引：238
|
作者：
SINGER, TP
CASTAGNOLI, N
RAMSAY, RR
TREVOR, AJ
机构：
[1] UNIV CALIF SAN FRANCISCO,DEPT BIOCHEM & BIOPHYS,SAN FRANCISCO,CA 94143
[2] UNIV CALIF SAN FRANCISCO,DEPT PHARM & PHARMACOL,SAN FRANCISCO,CA 94143
[3] VET ADM MED CTR,DEPT PHARM & PHARMACOL,SAN FRANCISCO,CA 94109
来源：
JOURNAL OF NEUROCHEMISTRY | 1987年 / 49卷 / 01期
关键词：
D O I：
10.1111/j.1471-4159.1987.tb03384.x
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
引用
收藏
页码：1 / 8
页数：8
相关论文
共 50 条
  • [41] MUTAGENICITY OF MPTP (1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE) AND ITS METABOLITES
    CASHMAN, JR
    TOXICOLOGY, 1987, 43 (02) : 173 - 182
  • [42] Promethazine protects against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine neurotoxicity
    Cleren, C
    Starkov, AA
    Calingasan, NY
    Lorenzo, BJ
    Chen, JY
    Beal, MF
    NEUROBIOLOGY OF DISEASE, 2005, 20 (03) : 701 - 708
  • [43] EFFECT OF 1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE (MPTP) IN GOLDFISH BRAIN
    POLI, A
    GUARNIERI, T
    FACCHINETTI, F
    VILLANI, L
    BRAIN RESEARCH, 1990, 534 (1-2) : 45 - 50
  • [44] ACCUMULATION OF 1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE IN CULTURED CEREBELLAR ASTROCYTES
    MARINI, AM
    LIPSKY, RH
    SCHWARTZ, JP
    KOPIN, IJ
    JOURNAL OF NEUROCHEMISTRY, 1992, 58 (04) : 1250 - 1258
  • [45] NEUROTOXIC ACTIONS OF 1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE IN MAN AND ANIMALS
    JENNER, P
    MARSDEN, CD
    HUMAN TOXICOLOGY, 1986, 5 (02): : 111 - 111
  • [46] Biochemical and immunohistological changes in the brain of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-treated mouse
    Araki, T
    Mikami, T
    Tanji, H
    Matsubara, M
    Imai, Y
    Mizugaki, M
    Itoyama, Y
    EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2001, 12 (03) : 231 - 238
  • [47] Neuroprotective mechanism of modafinil on Parkinson disease induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine
    Xiao, YL
    Fu, JM
    Dong, Z
    Yang, JQ
    Zeng, FX
    Zhu, LX
    He, BC
    ACTA PHARMACOLOGICA SINICA, 2004, 25 (03) : 301 - 305
  • [48] Neuroprotective mechanism of modafinil on Parkinson disease induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine
    Yan-li XIAO
    1Chongqing PharmaceuticalResearch Institute
    ActaPharmacologicaSinica, 2004, (03) : 47 - 51
  • [49] Levodopa-induced hyperactivity in mice treated with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine
    Nicholas, Anthony P.
    MOVEMENT DISORDERS, 2007, 22 (01) : 99 - 104
  • [50] ABILITY OF 1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE AND SOME OTHER PYRIDINE-DERIVATIVES TO CAUSE PARKINSONISM
    LERMONTOVA, NN
    SOLYAKOV, LS
    BACHURIN, SO
    TKACHENKO, SE
    SERKOVA, TP
    PETROVA, LN
    KALASHNIKOV, VV
    BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE, 1989, 107 (06) : 815 - 817
12345