NUTRITION AND PEDIATRIC RHEUMATIC DISEASES - HYPOTHESIS - CYTOKINES MODULATE NUTRITIONAL ABNORMALITIES IN RHEUMATIC DISEASES

被引：0
|
作者：
OSTROV, BE [1 ]
机构：
[1] PENN STATE UNIV,MILTON S HERSHEY MED CTR,CHILDRENS HOSP,HERSHEY MED CTR,DEPT PEDIAT,HERSHEY,PA 17033
来源：
JOURNAL OF RHEUMATOLOGY | 1992年 / 19卷
关键词：
JUVENILE RHEUMATOID ARTHRITIS; NUTRITIONAL STATUS; CYTOKINES;
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Growth abnormalities are common in pediatric rheumatic diseases. Studies suggest that effects of inflammation such as anorexia, and adipose and muscle tissue breakdown contribute to the nutritional and growth aberrations. The effects of the various cytokines produced during inflammation create a vicious cycle of anorexia and increased catabolism, and may be responsible for the nutritional deficits seen. In future, specific treatment with anticytokine monoclonal antibodies may block these effects, minimizing the nutritional consequences of inflammation.
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页码：49 / 53
页数：5
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