EFFECTS OF PYRIDOXAL 5'-PHOSPHATE ON PLASMA ALANINE AMINOTRANSFERASE DETERMINATIONS IN TOXICOLOGICAL STUDIES

被引：4

作者：

EVANS, GO ^{[1
]}

WHITEHORN, LC ^{[1
]}

机构：

[1] WELLCOME RES LABS, DRUG SAFETY EVALUAT, BECKENHAM BR3 3BS, KENT, ENGLAND

来源：

TOXICOLOGY LETTERS | 1995年 / 80卷 / 1-3期

关键词：

PLASMA; RAT; ALANINE AMINOTRANSFERASE; PYRIDOXAL 5'-PHOSPHATE;

D O I：

10.1016/0378-4274(95)03324-E

中图分类号：

R99 [毒物学（毒理学）];

学科分类号：

100405 ;

摘要：

Alanine aminotransferase activities (ALT) were measured in rat plasma samples with three different reagent formulations. The inclusion of pyridoxal 5'-phosphate in the reagent produced higher ALT values, and altered the statistical relationships between control and treatment groups in three studies where plasma ALT values were reduced by xenobiotics.

引用

页码：34 / 37

页数：4

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