共 50 条
- [41] Carrier-mediated hepatobiliary transport of a novel antifolate, N-[4-[(2,4-diamminopteridine-6-yl) methyl]-3,4-dihydro-2H-1,4-benzothiazin-7-yl]carbonyl-L- homoglutamic acid, in ratsDRUG METABOLISM AND DISPOSITION, 2001, 29 (04) : 394 - 400Han, YHKato, YWatanabe, YTerao, KAsoh, YSugiyama, Y
- [42] REACTION OF 3-(ACETOXYAMINO)QUINAZOLIN-4(3H)-ONES WITH ENOLIC BETA-DIKETONES - THE N-N BOND AS A CHIRAL AXIS IN N-(3,4-DIHYDRO-4-OXOQUINAZOLIN-3-YL)-N-ACYL-ALPHA-AMINOKETONES - REDUCTIVE AND BASE-CATALYZED CLEAVAGE OF THE N-N BOND IN N-ACETYL-N-(3,4-DIHYDRO-4-OXOQUINAZOLIN-3-YL)-ALPHA-AMINO-ACID ESTERSJOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, 1994, (21): : 3209 - 3216ATKINSON, RSEDWARDS, PJTHOMSON, GA
- [43] N-(6-Amino-3,4-dihydro-3-methyl-5-nitroso-4-oxopyrimidin-2-yl)-(S)-glutamic acid:: a three-dimensional framework structure built from O-H•••O, N-H•••O and O-H•••N hydrogen bondsACTA CRYSTALLOGRAPHICA SECTION C-CRYSTAL STRUCTURE COMMUNICATIONS, 2003, 59 : O210 - O212Mascarós, PAValero, MDGLow, JNGlidewell, C
- [44] SYNTHETIC STUDIES ON BETA-LACTAM ANTIBIOTICS .5. STEREOSELECTIVE SYNTHESIS OF 1,9B-DIHYDRO-2H,4H-2-OXO-AZETO [1,2-C] [1,3] BENZOXAZINE-4-CARBOXYLIC ACID-DERIVATIVESHETEROCYCLES, 1979, 12 (06) : 795 - 800KAMETANI, TKIGASAWA, KHIIRAGI, MWAKISAKA, KSUGI, HTANIGAWA, K
- [45] Synthesis of enantiomerically pure beta-amino acids from 2-tert-butyl-1-carbomethoxy-2,3-dihydro-4(1H)-pyrimidinone: (R)-3-amino-3-(p-methoxyphenyl)propionic acid - (1(2H)-pyrimidinecarboxylic acid, 2-(1,1-dimethylethyl)-3,4-dihydro-4-oxo, methyl ester, (R)- or (S)-)ORGANIC SYNTHESIS, VOL 73, 1996, 73 : 201 - 214Lakner, FJChu, KSNegrete, GRKonopelski, JP
- [46] Synthesis of 2-aryl-7-methoxy-2-trifluoromethyl-3,4-dihydro-2H-benzo[e][1,3]oxyoazin-4-ones during intermolecular cyclocondensation of N-(1-aryl-2,2,2-trifluoroethylidene)-O-(3-methoxyphenyl)urethanesZHURNAL ORGANICHESKOI KHIMII, 1996, 32 (03): : 476 - 477Vovk, MVPokholenko, AABolbut, AV
- [47] Synthesis of Tritiated N-[4-(2,4-Diaminopteridine-6-Methyl)- 3,4- Dihydro-2H-1,4-Benzothiazine-7-Carbonyl]$ MIN@L- Homo Glutamic Acid (MX-68)Journal of Labelled Compounds and Radiopharmaceuticals, 39 (05):Matsuoka, H.Kuroki, T.Yano, K.Takeda, Y.
- [48] Synthesis of N-{4-[(2,4-diamino-5-methyl-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-6-yl)thio]benzoyl}-L-glutamic acid and N-{4-[(2-amino-4-oxo-5-methyl-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-6-yl)thio]benzoyl}-L-glutamic acid as dual inhibitors of dihydrofolate reductase and thymidylate synthase and as potential antitumor agentsJOURNAL OF MEDICINAL CHEMISTRY, 2005, 48 (23) : 7215 - 7222Gangjee, ALin, XKisliuk, RLMcGuire, JJ
- [49] Synthesis of N-{4-[2-(2-amino-3,4-dihydro-4-oxo-7H-pyrrolo[2,3-(d)under-bar]pyrimidin-5-yl)ethyl]benzoyl}-L-glutamic acid (LY231514) and analoguesCHEMISTRY AND BIOLOGY OF PTERIDINES AND FOLATES 1997, 1997, : 83 - 91Taylor, ECKuhnt, DShih, CA
- [50] SYNTHESIS OF A NOVEL 5-DEAZA-5-THIA ANALOG OF TETRAHYDROFOLIC ACID, N-(P-([(2-AMINO-6,7-DIHYDRO-4-OXO-3H,8H-PYRIMIDO[5,4-B][1,4]THIAZIN-6-YL)METHYL]AMINO)BENZOYL)GLUTAMIC ACIDJOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, 1994, (07): : 833 - 836TOTANI, RSAKE, MHIROTA, KMAKI, Y