EVALUATION OF A COMMERCIAL MEASLES-VIRUS IMMUNOGLOBULIN-M ENZYME-IMMUNOASSAY

被引：10
|
作者：
MAYO, DR
BRENNAN, T
CORMIER, DP
HADLER, J
LAMB, P
机构：
[1] CONNECTICUT DEPT HLTH SERV,IMMUNIZAT PROGRAM,HARTFORD,CT 06144
[2] CONNECTICUT DEPT HLTH SERV,EPIDEMIOL SECT,HARTFORD,CT 06144
来源：
JOURNAL OF CLINICAL MICROBIOLOGY | 1991年 / 29卷 / 12期
关键词：
D O I：
10.1128/JCM.29.12.2865-2867.1991
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
Paired serum samples from 93 patients suspected of having measles were assayed for measles virus-specific immunoglobulin M (IgM) antibodies by an enzyme immunoassay (EIA), and the results were compared with results from a complement fixation assay and an EIA for measles virus IgG. By using significant serologic rises as the standard for comparison, the IgM EIA assay had a sensitivity of 85.7%, a specificity of 81.3%, a positive predictive value of 95.7%, and a negative predictive value of 54.2%. This assay can be expected to perform well in outbreak situations.
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页码：2865 / 2867
页数：3
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