TRANSDERMAL NITROGLYCERIN PREVENTS NONSTEROIDAL ANTIINFLAMMATORY DRUG GASTROPATHY

被引：14

作者：

BARRACHINA, MD ^{[1
]}

CALATAYUD, S ^{[1
]}

CANET, A ^{[1
]}

BELLO, R ^{[1
]}

DEROJAS, FD ^{[1
]}

GUTH, PH ^{[1
]}

ESPLUGUES, JV ^{[1
]}

机构：

[1] UNIV VALENCIA,FAC MED,DEPT FARMACOL,E-46010 VALENCIA,SPAIN

来源：

EUROPEAN JOURNAL OF PHARMACOLOGY | 1995年 / 281卷 / 02期

关键词：

NSAID (NONSTEROIDAL ANTIINFLAMMATORY DRUG); GASTRIC MUCOSAL INJURY; NITRIC OXIDE (NO);

D O I：

10.1016/0014-2999(95)00399-6

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

The application of a transdermal nitroglycerin patch (2-30 mu g/3 h/rat) protected, in a dose-dependent manner, the rat gastric mucosa against damage induced by the nonsteroidal anti-inflammatory agent indomethacin (20 mg/kg s.c.).

引用

页码：R3 / R4

页数：2

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