FREQUENCIES OF X-RAY-INDUCED CHROMOSOME TRANSLOCATIONS IN HUMAN PERIPHERAL LYMPHOCYTES AS DETECTED BY INSITU HYBRIDIZATION USING CHROMOSOME-SPECIFIC DNA LIBRARIES

被引：169
|
作者：
NATARAJAN, AT [1 ]
VYAS, RC [1 ]
DARROUDI, F [1 ]
VERMEULEN, S [1 ]
机构：
[1] INTERUNIV RES INST RADIOPATHOL & RADIAT PROTECT,JA COHEN INST,LEIDEN,NETHERLANDS
来源：
INTERNATIONAL JOURNAL OF RADIATION BIOLOGY | 1992年 / 61卷 / 02期
关键词：
D O I：
10.1080/09553009214550821
中图分类号：
Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
In situ hybridization with chromosome-specific DNA libraries was used to analyse radiation-induced stable translocations in human peripheral blood lymphocytes. These data were compared with radiation-induced unstable-type aberrations (dicentrics) in the same samples. The results indicate that far more stable aberrations are induced by radiation in comparison to unstable aberrations.
引用
收藏
页码：199 / 203
页数：5
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