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FREQUENCIES OF X-RAY-INDUCED CHROMOSOME TRANSLOCATIONS IN HUMAN PERIPHERAL LYMPHOCYTES AS DETECTED BY INSITU HYBRIDIZATION USING CHROMOSOME-SPECIFIC DNA LIBRARIES
被引:169
|作者:
NATARAJAN, AT
[1
]
VYAS, RC
[1
]
DARROUDI, F
[1
]
VERMEULEN, S
[1
]
机构:
[1] INTERUNIV RES INST RADIOPATHOL & RADIAT PROTECT,JA COHEN INST,LEIDEN,NETHERLANDS
关键词:
D O I:
10.1080/09553009214550821
中图分类号:
Q [生物科学];
学科分类号:
07 ;
0710 ;
09 ;
摘要:
In situ hybridization with chromosome-specific DNA libraries was used to analyse radiation-induced stable translocations in human peripheral blood lymphocytes. These data were compared with radiation-induced unstable-type aberrations (dicentrics) in the same samples. The results indicate that far more stable aberrations are induced by radiation in comparison to unstable aberrations.
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页码:199 / 203
页数:5
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