FREQUENCIES OF X-RAY-INDUCED CHROMOSOME TRANSLOCATIONS IN HUMAN PERIPHERAL LYMPHOCYTES AS DETECTED BY INSITU HYBRIDIZATION USING CHROMOSOME-SPECIFIC DNA LIBRARIES

被引:169
|
作者
NATARAJAN, AT [1 ]
VYAS, RC [1 ]
DARROUDI, F [1 ]
VERMEULEN, S [1 ]
机构
[1] INTERUNIV RES INST RADIOPATHOL & RADIAT PROTECT,JA COHEN INST,LEIDEN,NETHERLANDS
关键词
D O I
10.1080/09553009214550821
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
In situ hybridization with chromosome-specific DNA libraries was used to analyse radiation-induced stable translocations in human peripheral blood lymphocytes. These data were compared with radiation-induced unstable-type aberrations (dicentrics) in the same samples. The results indicate that far more stable aberrations are induced by radiation in comparison to unstable aberrations.
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页码:199 / 203
页数:5
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