THEORETICAL MODEL OF CARBON NANOTUBES AS DELIVERY TO FLUOROURACIL (Anticancer)

被引：0
|
作者：
Al-anber, Mohanned J. [1 ]
Al-Masoudi, Najim A. [2 ]
机构：
[1] Basrah Univ, Coll Sci, Dept Phys, Basrah City, Iraq
[2] Basrah Univ, Coll Sci, Dept Chem, Basrah City, Iraq
来源：
REVISTA COLOMBIANA DE QUIMICA | 2012年 / 41卷 / 02期
关键词：
anticancer; drug delivery; CNT; fluorouracil; semi-empirical; binding energy;
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The quantum modeling interaction properties of fluorouracil radicals on the single walled carbon nanotubes surface is researched via MNDO/d calculations. We have studied the effect of diameter, length, position and rotational characteristics of CNT on binding fluorouracil. Our results suggest that the binding energy is lower as the CNT diameter increases, while as the CNT length increases the binding energy initially increases and then slightly increases.
引用
收藏
页码：299 / 309
页数：11
相关论文
共 50 条
  • [1] Carbon Nanotubes for Delivery of Quercetin as Anticancer Drug: Theoretical Study
    Daneshmehr, S.
    [J]. 5TH INTERNATIONAL BIENNIAL CONFERENCE ON ULTRAFINE GRAINED AND NANOSTRUCTURED MATERIALS, UFGNSM15, 2015, 11 : 131 - 136
  • [2] Boron nitride nanotubes for delivery of 5-fluorouracil as anticancer drug: a theoretical study
    Shayan, Kolsoom
    Nowroozi, Alireza
    [J]. APPLIED SURFACE SCIENCE, 2018, 428 : 500 - 513
  • [3] Carbon nanotubes in the delivery of anticancer herbal drugs
    Jogi, Hardi
    Maheshwari, Rahul
    Raval, Nidhi
    Kuche, Kaushik
    Tambe, Vishakha
    Mak, Kit-Kay
    Pichika, Mallikarjuna Rao
    Tekade, Rakesh Kumar
    [J]. NANOMEDICINE, 2018, 13 (10) : 1187 - 1220
  • [4] Functionalized carbon nanotubes for anticancer drug delivery
    Lay, Chee Leng
    Liu, Jing
    Liu, Ye
    [J]. EXPERT REVIEW OF MEDICAL DEVICES, 2011, 8 (05) : 561 - 566
  • [5] Carbon nanotubes in drug delivery: Focus on anticancer therapies
    Kiran, A. V. V. V. Ravi
    Kumari, G. Kusuma
    Krishnamurthy, Praveen T.
    [J]. JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY, 2020, 59
  • [6] Effects of carbon nanotubes on properties of the fluorouracil anticancer drug: DFT studies of a CNT-fluorouracil compound
    Mirzaei, M.
    [J]. INTERNATIONAL JOURNAL OF NANO DIMENSION, 2013, 3 (03) : 175 - 179
  • [7] Recent Advances in Carbon Nanotubes as Delivery Systems for Anticancer Drugs
    Iannazzo, Daniela
    Piperno, Anna
    Pistone, Alessandro
    Grassi, Giovanni
    Galvagno, Signorino
    [J]. CURRENT MEDICINAL CHEMISTRY, 2013, 20 (11) : 1333 - 1354
  • [8] Ligand Mediated Carbon Nanotubes Based Delivery of an Anticancer Agent
    Mangla, B.
    Patel, Kuldeep S.
    Kumar, P.
    Kulkarni, Giriraj T.
    [J]. LATIN AMERICAN JOURNAL OF PHARMACY, 2017, 36 (10): : 2081 - 2091
  • [9] Theoretical study of the interaction between carbon nanotubes and carboplatin anticancer molecules
    El Khalifi, M.
    Duverger, E.
    Boulahdour, H.
    Picaud, F.
    [J]. ANALYTICAL METHODS, 2015, 7 (24) : 10145 - 10150
  • [10] Carbon nanotubes as a novel drug delivery system for anticancer therapy: a review
    Kushwaha, Swatantra Kumar Singh
    Ghoshal, Saurav
    Rai, Awani Kumar
    Singh, Satyawan
    [J]. BRAZILIAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2013, 49 (04) : 629 - 643
12345