Carbon nanotubes in the delivery of anticancer herbal drugs

被引：24

作者：

Jogi, Hardi ^{[1
]}

Maheshwari, Rahul ^{[1
]}

Raval, Nidhi ^{[1
]}

Kuche, Kaushik ^{[1
]}

Tambe, Vishakha ^{[1
]}

Mak, Kit-Kay ^{[2
]}

Pichika, Mallikarjuna Rao ^{[3
]}

Tekade, Rakesh Kumar ^{[1
]}

机构：

[1] NIPER Ahmedabad, Opposite Air Force Stn Palaj, Gandhinagar 382355, Gujarat, India

[2] Int Med Univ, Sch Postgrad Studies & Res, Kuala Lumpur, Malaysia

[3] Int Med Univ, Sch Pharm, Dept Pharmaceut Chem, Kuala Lumpur, Malaysia

来源：

NANOMEDICINE | 2018年 / 13卷 / 10期

关键词：

anticancer herbal biomolecules; biopharmaceutics; cancer; carbon nanotubes; nanotechnology; novel drug delivery system; patents; regulatory and clinical status; ORIDONIN INDUCES APOPTOSIS; CANCER-CELL LINES; IN-VITRO; ANTIOXIDANT ACTIVITY; GALLIC ACID; APOPTOGENIC PROPERTIES; PLGA NANOPARTICLES; MOLECULAR-DYNAMICS; NATURAL-PRODUCTS; BETULINIC ACID;

D O I：

10.2217/nnm-2017-0397

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Cancer is estimated to be a significant health problem of the 21st century. The situation gets even tougher when it comes to its treatment using chemotherapy employing synthetic anticancer molecules with numerous side effects. Recently, there has been a paradigm shift toward the adoption of herbal drugs for the treatment of cancer. In this context, a suitable delivery system is principally warranted to deliver these herbal biomolecules specifically at the tumorous site. To achieve this goal, carbon nanotubes (CNTs) have been widely explored to deliver anticancer herbal molecules with improved therapeutic efficacy and safety. This review uniquely expounds the biopharmaceutical, clinical and safety aspects of different anticancer herbal drugs delivered through CNTs with a cross-talk on their outcomes. This review will serve as a one-stop-shop for the readers on various anticancer herbal drugs delivered through CNTs as a futuristic delivery device.

引用

页码：1187 / 1220

页数：34

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