AN IMPROVED SYNTHESIS OF 3,6-DIAMINO-1,2,4,5-TETRAZINE .1.

被引：18
|
作者：
COBURN, MD
OTT, DG
机构：
[1] University of California, Los Alamos National Laboratory, Los Alamos, New Mexico
来源：
JOURNAL OF HETEROCYCLIC CHEMISTRY | 1990年 / 27卷 / 07期
关键词：
D O I：
10.1002/jhet.5570270717
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Treatment of 1,3-diaminoguanidine monohydrochloride (1) with 2,4-pentanedione (2) in alcohols under carefully controlled conditions gave 3,6-diamino-1,2-dihydro-1,2,4,5-tetrazine monohydrochloride (3) in 45-50% yields along with 3,5-dimethyl-1H-pyrazole (4) and its hydrochloride 5. Oxidation of 3 with sodium perborate produced 3,6-diamino-1,2,4,5-tetrazine (6) in quantitative yield.
引用
收藏
页码：1941 / 1945
页数：5
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