Music therapists select, design, and facilitate music experiences with clients' primary health needs in mind. The focus of this article is the first step in this process-the selection of music experiences. The four music therapy methods, as defined by Bruscia (2014) (re-creation, composition, improvisation, and receptive or listening experiences), provide myriad variations through which a therapist might engage clients in musicking for therapeutic benefit. To determine which particular type of music experience will most benefit a client's treatment process at any given time requires thoughtful consideration of a variety of factors and issues, including ethics, clinical efficacy, contraindications, orientation of the therapist and/or treatment facility, cultural awareness, and client preferences and readiness. The article concludes with a series of questions that therapists may find useful toward thinking through the general considerations presented as well as others specific to the needs of one's clientele.