Chronic inflammatory demyelinating polyneuropathy triggered by interferon-alpha for chronic hepatitis B virus infection

被引：0

作者：

Sakaguchi, Hideya ^{[1
]}

Yamashita, Satoshi ^{[1
]}

Ueda, Akihiko ^{[1
]}

Sada, Hiromi ^{[1
]}

Ikeda, Tokunori ^{[1
]}

Hirahara, Tomoo ^{[1
]}

Honda, Shoji ^{[1
]}

Kimura, En ^{[1
]}

Yamashita, Taro ^{[1
]}

Maeda, Yasushi ^{[1
]}

Hirano, Teruyuki ^{[1
]}

Uchino, Makoto ^{[1
]}

机构：

[1] Kumamoto Univ, Grad Sch Med Sci, Dept Neurol, Kumamoto, Japan

来源：

NEUROLOGY AND CLINICAL NEUROSCIENCE | 2015年 / 3卷 / 01期

关键词：

chronic hepatitis B virus infection; chronic inflammatory demyelinating polyneuropathy; corticosteroid; interferon-alpha; intravenous immunoglobulin;

D O I：

10.1111/ncn3.136

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Interferon-alpha has been widely used for treatment of chronic hepatitis and some malignancies. Several autoimmune diseases have been reported to be induced by interferon-alpha, but chronic inflammatory demyelinating polyneuropathy is rare. Here, we report a chronic hepatitis B patient who developed chronic inflammatory demyelinating polyneuropathy after receiving interferon-alpha treatment. After withdrawal of interferon-alpha, neurological symptoms continued to progress, but the symptoms improved after intravenous immunoglobulin treatment. This case provides further immunological insight into the correlation between chronic inflammatory demyelinating polyneuropathy and Interferon-alpha.

引用

页码：36 / 38

页数：3

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