Chronic inflammatory demyelinating polyneuropathy triggered by interferon-alpha for chronic hepatitis B virus infection

被引：0
|
作者：
Sakaguchi, Hideya [1 ]
Yamashita, Satoshi [1 ]
Ueda, Akihiko [1 ]
Sada, Hiromi [1 ]
Ikeda, Tokunori [1 ]
Hirahara, Tomoo [1 ]
Honda, Shoji [1 ]
Kimura, En [1 ]
Yamashita, Taro [1 ]
Maeda, Yasushi [1 ]
Hirano, Teruyuki [1 ]
Uchino, Makoto [1 ]
机构：
[1] Kumamoto Univ, Grad Sch Med Sci, Dept Neurol, Kumamoto, Japan
来源：
NEUROLOGY AND CLINICAL NEUROSCIENCE | 2015年 / 3卷 / 01期
关键词：
chronic hepatitis B virus infection; chronic inflammatory demyelinating polyneuropathy; corticosteroid; interferon-alpha; intravenous immunoglobulin;
D O I：
10.1111/ncn3.136
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
Interferon-alpha has been widely used for treatment of chronic hepatitis and some malignancies. Several autoimmune diseases have been reported to be induced by interferon-alpha, but chronic inflammatory demyelinating polyneuropathy is rare. Here, we report a chronic hepatitis B patient who developed chronic inflammatory demyelinating polyneuropathy after receiving interferon-alpha treatment. After withdrawal of interferon-alpha, neurological symptoms continued to progress, but the symptoms improved after intravenous immunoglobulin treatment. This case provides further immunological insight into the correlation between chronic inflammatory demyelinating polyneuropathy and Interferon-alpha.
引用
收藏
页码：36 / 38
页数：3
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