Quantitative Study of Cellular Mechanisms of HIV Infection's Pathogenesis

CD4 lymphocyte affection underlies in HIV/AIDS infection pathogenesis. In this work we consider some questions of quantitative analysis of CD4 lymphocyte activity at the norm and HIV infection by mathematical modeling. Functional-differential equations for studying regulatory mechanisms of dynamics of CD4 lymphocyte's cellular communities' number have been developed. Results of the qualitative analysis, illustrating possibility of using the developed equations for studying mechanisms of HIV infection's pathogenesis without attraction of the "Hayflick limit" concept are presented. Some questions concerning choice of control ways of dynamics behavior of CD4 lymphocyte's cellular communities' number during HIV infection's pathogenesis are considered.