HEME CATABOLISM IN CULTURED-HEPATOCYTES - EVIDENCE THAT HEME OXYGENASE IS THE PREDOMINANT PATHWAY AND THAT A PROPORTION OF SYNTHESIZED HEME IS CONVERTED RAPIDLY TO BILIVERDIN

被引：37
|
作者：
LINCOLN, BC
AW, TY
BONKOVSKY, HL
机构：
[1] EMORY UNIV,DEPT BIOCHEM,1364 CLIFTON RD NE,ATLANTA,GA 30322
[2] EMORY UNIV,DEPT MED,ATLANTA,GA 30322
来源：
BIOCHIMICA ET BIOPHYSICA ACTA | 1989年 / 992卷 / 01期
关键词：
D O I：
10.1016/0304-4165(89)90049-4
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
引用
收藏
页码：49 / 58
页数：10
相关论文
共 36 条
  • [31] Ascorbic acid partly antagonizes resveratrol mediated heme oxygenase-1 but not paraoxonase-1 induction in cultured hepatocytes - role of the redox-regulated transcription factor Nrf2
    Wagner, Anika E.
    Boesch-Saadatmandi, Christine
    Breckwoldt, Dorothea
    Schrader, Charlotte
    Schmelzer, Constance
    Doering, Frank
    Hashida, Koji
    Hori, Osamu
    Matsugo, Seiichi
    Rimbach, Gerald
    BMC COMPLEMENTARY AND ALTERNATIVE MEDICINE, 2010, 11
  • [32] Ascorbic acid partly antagonizes resveratrol mediated heme oxygenase-1 but not paraoxonase-1 induction in cultured hepatocytes - role of the redox-regulated transcription factor Nrf2
    Anika E Wagner
    Christine Boesch-Saadatmandi
    Dorothea Breckwoldt
    Charlotte Schrader
    Constance Schmelzer
    Frank Döring
    Koji Hashida
    Osamu Hori
    Seiichi Matsugo
    Gerald Rimbach
    BMC Complementary and Alternative Medicine, 11
  • [33] Gliotoxin reduces the severity of trinitrobenzene sulfonic acid-induced colitis in mice:: Evidence of the connection between heme oxygenase-1 and the nuclear factor-κB pathway in vitro and in vivo
    Jun, Chang-Duk
    Kim, Yurim
    Choi, Eun-Yong
    Kim, Minsun
    Park, Byungrim
    Youn, Byungsoo
    Yu, Kangyeol
    Choi, Kyu-Sil
    Yoon, Kwon-Ha
    Choi, Suck-Chei
    Lee, Myeung-Su
    Park, Kie-In
    Choi, Minkyu
    Chung, Yeuntai
    Oh, Jaemin
    INFLAMMATORY BOWEL DISEASES, 2006, 12 (07) : 619 - 629
  • [34] 4-Methylcatechol-induced heme oxygenase-1 exerts a protective effect against oxidative stress in cultured neural stem/progenitor cells via PI3 kinase/Akt pathway
    Furukawa, Yoshiko
    Urano, Tomomi
    Minamimura, Misato
    Nakajima, Mitsunari
    Okuyama, Satoshi
    Furukawa, Shoei
    BIOMEDICAL RESEARCH-TOKYO, 2010, 31 (01): : 45 - 52
  • [35] Induction of heme oxygenase-1 (HO-1) and NAD[P]H:: Quinone oxidoreductase 1 (NQO1) by a phenolic antioxidant, butylated hydroxyanisole (BHA) and its metabolite, tert-butylhydroquinone (tBHQ) in primary-cultured human and rat hepatocytes
    Keum, Young-Sam
    Han, Yong-Hae
    Liew, Celine
    Kim, Jung-Hwan
    Xu, Changjiang
    Yuan, Xiaoling
    Shakarjian, Michael P.
    Chong, Saeho
    Kong, Ah-Ng
    PHARMACEUTICAL RESEARCH, 2006, 23 (11) : 2586 - 2594
  • [36] Induction of Heme Oxygenase-1 (HO-1) and NAD[P]H: Quinone Oxidoreductase 1 (NQO1) by a Phenolic Antioxidant, Butylated Hydroxyanisole (BHA) and Its Metabolite, tert-Butylhydroquinone (tBHQ) in Primary-Cultured Human and Rat Hepatocytes
    Young-Sam Keum
    Yong-Hae Han
    Celine Liew
    Jung-Hwan Kim
    Changjiang Xu
    Xiaoling Yuan
    Michael P. Shakarjian
    Saeho Chong
    Ah-Ng Kong
    Pharmaceutical Research, 2006, 23 : 2586 - 2594
1234