Renal transplantation is the treatment of choice for patients with end stage renal disease. Better comprehension of the rejection response, improved preservation organs, judicious use of ciclosporine, the application of anti-lymphocytes agents for the prevention and treatment of rejection, and specific protocols for the prevention and treatment of infection have all contributed to the recent improvement in outcome after renal transplantation. The causes of kidney dysfunction after transplantation are numerous. Currently, no medical imaging process allows the formal diagnosis of kidney rejection. Only histological findings from kidney biopsy can be used.