Two cell configurations involving a rotating bioreactor and a stationary platinum-ring amperometric detector are compared with regard to data produced by continuous-flow and continuous-flow/stopped-flow/continuous-flow operations. In addition to data collection, six kinetic-based approaches to data treatment are also compared. The approaches to data treatment considered here are: (1) the initial rate measurement, (2) integration of the signal time profile, (3) a linear steady-state predictive approach, (4) a nonlinear steady-state predictive approach, (5) a single measurement fixed-time mode, and (6) a multimeasurement fixed-time mode.
