2ND CONSERVED DOMAIN OF GP120 IS IMPORTANT FOR HIV INFECTIVITY AND ANTIBODY NEUTRALIZATION

被引：244
|
作者：
HO, DD
KAPLAN, JC
RACKAUSKAS, IE
GURNEY, ME
机构：
[1] MASSACHUSETTS GEN HOSP,INFECT DIS UNIT,BOSTON,MA 02114
[2] HARVARD UNIV,SCH MED,BOSTON,MA 02115
[3] UNIV CALIF LOS ANGELES,SCH MED,LOS ANGELES,CA 90024
[4] UNIV CHICAGO,DEPT PHARMACOL & PHYSIOL SCI,CHICAGO,IL 60637
来源：
SCIENCE | 1988年 / 239卷 / 4843期
关键词：
D O I：
10.1126/science.2830667
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
引用
收藏
页码：1021 / 1023
页数：3
相关论文
共 50 条
  • [41] IDENTIFICATION AND CHARACTERIZATION OF A NEUTRALIZATION SITE WITHIN THE 2ND VARIABLE REGION OF HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 GP120
    FUNG, MSC
    SUN, CRY
    GORDON, WL
    LIOU, RS
    CHANG, TW
    SUN, WNC
    DAAR, ES
    HO, DD
    JOURNAL OF VIROLOGY, 1992, 66 (02) : 848 - 856
  • [42] IDENTIFICATION OF CROSS-REACTIVE CONSERVED REGIONS IN HIV-1 GP120
    VERONESE, FD
    RAHMAN, R
    KALYANARAMAN, VS
    NAIR, BC
    GALLO, RC
    SARNGADHARAN, MG
    AIDS RESEARCH AND HUMAN RETROVIRUSES, 1990, 6 (01) : 32 - 32
  • [43] Heparin-binding domain of human fibronectin binds HIV-1 gp120/160 and reduces virus infectivity
    Bozzini, S
    Falcone, V
    Conaldi, PG
    Visai, L
    Biancone, L
    Dolei, A
    Toniolo, A
    Speziale, P
    JOURNAL OF MEDICAL VIROLOGY, 1998, 54 (01) : 44 - 53
  • [44] RESTRICTION OF SERUM ANTIBODY REACTIVITY TO THE V3 NEUTRALIZING DOMAIN OF HIV GP120 WITH PROGRESSION TO AIDS
    PAGE, M
    VELLA, C
    CORCORAN, T
    DILGER, P
    LING, C
    HEATH, A
    THORPE, R
    AIDS, 1992, 6 (05) : 441 - 446
  • [45] Patterns of conserved gp120 epitope presentation on attached HIV-1 virions
    Mengistu, Meron
    Tang, Ai-hui
    Foulke, James S., Jr.
    Blanpied, Thomas A.
    Gonzalez, Mileidy W.
    Spouge, John L.
    Gallo, Robert C.
    Lewis, George K.
    DeVico, Anthony L.
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2017, 114 (46) : E9893 - E9902
  • [46] Involvement of the HIV-1 external envelope glycoprotein 120 (gp120) C2 region in gp120 oligomerization
    Seddiki, N
    Bouhlal, H
    Rabehi, L
    Benjouad, A
    Devaux, C
    Gluckman, JC
    Gattegno, L
    BIOCHIMICA ET BIOPHYSICA ACTA-PROTEIN STRUCTURE AND MOLECULAR ENZYMOLOGY, 1997, 1340 (02): : 277 - 282
  • [47] A conservative domain shared by HIV gp120 and EIAV gp90: Implications for HIV vaccine design
    Li, HG
    Zhang, XY
    Fan, XJ
    Shen, T
    Tong, X
    Shen, RX
    Shao, YM
    AIDS RESEARCH AND HUMAN RETROVIRUSES, 2005, 21 (12) : 1057 - 1059
  • [48] PRELIMINARY CRYSTALLOGRAPHIC ANALYSIS OF THE FAB FRAGMENT OF AN ANTIBODY AGAINST HIV GP120
    VYAS, MN
    VYAS, NK
    LIOU, RS
    CHANG, TW
    QUIOCHO, FA
    JOURNAL OF MOLECULAR BIOLOGY, 1990, 214 (01) : 23 - 24
  • [49] Antibody repertoire against HIV-1 gp120 triggered in nude and normal mice by GM-CSF/gp120 immunization
    del Real, G
    Llorente, M
    Lucas, P
    Kremer, L
    Torán, JL
    Martínez, C
    MOLECULAR IMMUNOLOGY, 1999, 36 (11-12) : 721 - 731
  • [50] Optimization of the Outer Domain of gp120 as an HIV-1 Vaccine Immunogen
    Xu, L.
    Boyington, J. C.
    Zhou, T.
    Zhu, J.
    Wu, L.
    Louder, M. K.
    Akahata, W.
    Kwong, P. D.
    Mascola, J. R.
    Yang, Z.
    Nabel, G. J.
    AIDS RESEARCH AND HUMAN RETROVIRUSES, 2010, 26 (10) : A166 - A167
12345