Hepatitis E virus infections in humans and animals

被引：26

作者：

Song, Young-Jo ^{[1
]}

Park, Woo-Jung ^{[1
]}

Park, Byung-Joo ^{[1
]}

Lee, Joong-Bok ^{[1
]}

Park, Seung-Yong ^{[1
]}

Song, Chang-Seon ^{[1
]}

Lee, Nak-Hyung ^{[1
]}

Seo, Kun-Ho ^{[2
]}

Kang, Young-Sun ^{[3
]}

Choi, In-Soo ^{[1
,4
]}

机构：

[1] Konkuk Univ, Coll Vet Med, Dept Infectious Dis, 263 Achasan Ro, Seoul 143701, South Korea

[2] Konkuk Univ, Coll Vet Med, Dept Publ Hlth, Seoul, South Korea

[3] Konkuk Univ, SMART Inst Adv Biomed Sci, Dept Biomed Sci & Technol, Seoul, South Korea

[4] Konkuk Univ, Coll Vet Med, Vet Sci Res Inst, Seoul, South Korea

来源：

CLINICAL AND EXPERIMENTAL VACCINE RESEARCH | 2014年 / 3卷 / 01期

关键词：

Hepatitis E virus; Zoonoses; Animals; Humans; Vaccines;

D O I：

10.7774/cevr.2014.3.1.29

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Hepatitis E has traditionally been considered an endemic disease of developing countries. It generally spreads through contaminated water. However, seroprevalence studies have shown that hepatitis E virus (HEV) infections are not uncommon in industrialized countries. In addition, the number of autochthonous hepatitis E cases in these countries is increasing. Most HEV infections in developed countries can be traced to the ingestion of contaminated raw or undercooked pork meat or sausages. Several animal species, including pigs, are known reservoirs of HEV that transmit the virus to humans. HEVs are now recognized as an emerging zoonotic agent. In this review, we describe the general characteristics of HEVs isolated from humans and animals, the risk factors for human HEV infection, and the current status of human vaccine development.

引用

页码：29 / 36

页数：8

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