Profile of infliximab in the treatment of pediatric Crohn's disease

被引：1
|
作者：
Kierkus, Jaroslaw [1 ]
Szymanska, Edyta [2 ]
Oracz, Grzegorz [1 ]
Wiernicka, Anna [1 ]
Dadalski, Maciej [1 ]
机构：
[1] Childrens Mem Hlth Inst, Dept Gastroenterol Hepatol Feeding Disorders & Pe, Al Dzieci Polskich 20, PL-04730 Warsaw, Poland
[2] Childrens Mem Hlth Inst, Dept Pediat Nutr & Metab Disorders, Warsaw, Poland
来源：
PEDIATRIC HEALTH MEDICINE AND THERAPEUTICS | 2015年 / 6卷
关键词：
infliximab; Crohn's disease; children; biologic therapy; anti-TNF-agents;
D O I：
10.2147/PHMT.S64943
中图分类号：
R72 [儿科学];
学科分类号：
100202 ;
摘要：
In recent years, a novel biologic therapy with monoclonal antibodies against tumor necrosis factor-alpha has revolutionized the treatment of Crohn's disease. Infliximab, the first biologic agent, has been demonstrated to considerably improve both clinical and endoscopic outcomes. In view of the growing popularity of infliximab in the management of Crohn's disease, we review the profile of the agent in the treatment of this disease in a pediatric setting.
引用
收藏
页码：79 / 85
页数：7
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