Profile of infliximab in the treatment of pediatric Crohn's disease

被引：1
|
作者：
Kierkus, Jaroslaw [1 ]
Szymanska, Edyta [2 ]
Oracz, Grzegorz [1 ]
Wiernicka, Anna [1 ]
Dadalski, Maciej [1 ]
机构：
[1] Childrens Mem Hlth Inst, Dept Gastroenterol Hepatol Feeding Disorders & Pe, Al Dzieci Polskich 20, PL-04730 Warsaw, Poland
[2] Childrens Mem Hlth Inst, Dept Pediat Nutr & Metab Disorders, Warsaw, Poland
来源：
PEDIATRIC HEALTH MEDICINE AND THERAPEUTICS | 2015年 / 6卷
关键词：
infliximab; Crohn's disease; children; biologic therapy; anti-TNF-agents;
D O I：
10.2147/PHMT.S64943
中图分类号：
R72 [儿科学];
学科分类号：
100202 ;
摘要：
In recent years, a novel biologic therapy with monoclonal antibodies against tumor necrosis factor-alpha has revolutionized the treatment of Crohn's disease. Infliximab, the first biologic agent, has been demonstrated to considerably improve both clinical and endoscopic outcomes. In view of the growing popularity of infliximab in the management of Crohn's disease, we review the profile of the agent in the treatment of this disease in a pediatric setting.
引用
收藏
页码：79 / 85
页数：7
相关论文
共 50 条
  • [1] INFLIXIMAB FOR PEDIATRIC CROHN'S DISEASE
    Hoffman, I.
    Vermeire, S.
    Van Assche, G.
    Rutgeerts, P.
    [J]. DRUGS OF TODAY, 2008, 44 (08) : 615 - 628
  • [2] Efficacy of early treatment with infliximab in pediatric Crohn’s disease
    Jong Seung Lee
    Jee Hyun Lee
    Ji Hyuk Lee
    Hye Jin Lee
    Mi Jin Kim
    Hae Jeong Lee
    Yon Ho Choe
    [J]. World Journal of Gastroenterology, 2010, 16 (14) : 1776 - 1781
  • [3] Efficacy of early treatment with infliximab in pediatric Crohn's disease
    Lee, Jong Seung
    Lee, Jee Hyun
    Lee, Ji Hyuk
    Lee, Hye Jin
    Kim, Mi Jin
    Lee, Hae Jeong
    Choe, Yon Ho
    [J]. WORLD JOURNAL OF GASTROENTEROLOGY, 2010, 16 (14) : 1776 - 1781
  • [4] Infliximab (REMICADE) therapy in the treatment of pediatric Crohn's disease
    Baldassano, R
    Braegger, CP
    Escher, JC
    DeWoody, K
    Hendricks, DF
    Keenan, GF
    Winter, HS
    [J]. AMERICAN JOURNAL OF GASTROENTEROLOGY, 2003, 98 (04): : 833 - 838
  • [5] The use of infliximab in pediatric Crohn's Disease
    Khan, S
    Henderson, WA
    Kocoshis, SA
    Goyal, A
    Di Lorenzo, C
    [J]. GASTROENTEROLOGY, 2001, 120 (05) : A210 - A210
  • [6] Infliximab therapy for pediatric Crohn's disease
    Veres, Gabor
    Baldassano, Robert N.
    Mamula, Petar
    [J]. EXPERT OPINION ON BIOLOGICAL THERAPY, 2007, 7 (12) : 1869 - 1880
  • [7] Infliximab therapy for pediatric Crohn's disease
    Oliva-Hemker, M
    Roper, S
    Cuffari, C
    Lake, A
    Wilson, L
    Leibowitz, I
    Duffy, L
    Tuchman, D
    [J]. GASTROENTEROLOGY, 2002, 122 (04) : A612 - A613
  • [8] Treatment with infliximab for pediatric Crohn's disease: Nationwide survey of Japan
    Hosoi, Kenji
    Ohtsuka, Yoshikazu
    Fujii, Tohru
    Kudo, Takahiro
    Matsunaga, Nobuaki
    Tomomasa, Takeshi
    Tajiri, Hitoshi
    Kunisaki, Reiko
    Ishige, Takashi
    Yamada, Hiroyuki
    Arai, Katsuhiro
    Yoden, Atsushi
    Ushijima, Kosuke
    Aomatsu, Tomoki
    Nagata, Satoru
    Uchida, Keiichi
    Takeuchi, Kazuo
    Shimizu, Toshiaki
    [J]. JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 2017, 32 (01) : 114 - 119
  • [9] Infliximab: A Review of its use in the Treatment of Pediatric Crohn's Disease
    Broder, Arkady
    Rosh, Joel R.
    [J]. CLINICAL MEDICINE INSIGHTS-THERAPEUTICS, 2010, 2 : 235 - 243
  • [10] Treatment of Crohn's disease with infliximab
    Garnett, WR
    Yunker, N
    [J]. AMERICAN JOURNAL OF HEALTH-SYSTEM PHARMACY, 2001, 58 (04) : 307 - 316
12345