Neoadjuvant therapy for resectable and borderline resectable pancreatic cancer

被引:4
|
作者
Kumar, Rachit [1 ]
Jabbour, Salma K. [2 ]
机构
[1] Johns Hopkins Univ, Sidney Kimmel Comprehens Canc Ctr, Dept Radiat Oncol & Mol Radiat Sci, Baltimore, MD USA
[2] Rutgers State Univ, Robert Wood Johnson Med Sch, Rutgers Canc Inst New Jersey, Dept Radiat Oncol, 195 Little Albany St, New Brunswick, NJ 08903 USA
关键词
Pancreatic cancer; Neoadjuvant therapy; Radiation therapy; Resectable; Borderline resectable;
D O I
10.1007/s13566-013-0120-9
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Neoadjuvant chemoradiation for resectable and borderline resectable pancreatic cancer has been widely investigated in the past two decades. Research demonstrates that this therapy may help improve surgical margins, reduce rates of lymph node positivity, allow for earlier initiation of systemic therapy, and select for patients with aggressive disease in whom surgery may not be warranted. This review presents the data for neoadjuvant chemoradiation in pancreatic cancer with a focus on resectable and borderline resectable disease.
引用
收藏
页码:353 / 367
页数:15
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