Role of the antioxidants in cancer prevention

被引:15
|
作者
Llacuna, Laura [1 ]
Mach, Nuria [1 ,2 ]
机构
[1] UOC, Estudis Ciencies Salut, Barcelona, Spain
[2] Wageningen UR Livestock Res, Anim Breeding & Genom Ctr, Lelystad, Netherlands
来源
关键词
Cancer; Free radicals; Antioxidant; Lysozyme; Glutathione;
D O I
10.1016/S2173-1292(12)70067-4
中图分类号
R15 [营养卫生、食品卫生]; TS201 [基础科学];
学科分类号
100403 ;
摘要
The nature of the association between free radicals and cancer is complex and paradoxical, as it seems that free radicals and oxidative stress can induce cancer, but at the same time the transformed cells, that is, the cancer cells generate more free radicals than normal cells. Endogenous antioxidant compounds, including glutathione and lysozyme, can limit the effects of oxidative stress, but these systems can be quickly saturated by high amounts of free radicals. It is important to increase the cellular levels of antioxidants that could provide protection against possible adverse agents that can cause a cell cancer. A good diet and the knowledge of several compounds of foods with antioxidant effects may be helpful to prevent cancer disease. (C) 2011 AsociaciOn Espanola de Dietistas-Nutricionistas. Published by Elsevier Espana, S.L. All rights reserved.
引用
收藏
页码:16 / 24
页数:9
相关论文
共 50 条
  • [31] DNA oxidation products, antioxidants status, and cancer prevention
    Thompson, HJ
    JOURNAL OF NUTRITION, 2004, 134 (11): : 3186S - 3187S
  • [32] Antioxidants in the Prevention of Colorectal Cancer - A Meta-Analysis
    Pais, Raluca
    Dechartres, Agnes
    Durieux, Pierre
    Dumitrascu, Dan Lucian
    GASTROENTEROLOGY, 2010, 138 (05) : S351 - S352
  • [33] INVESTIGATION OF THE BIOCHEMICAL MECHANISM OF ACTION OF ANTIOXIDANTS IN THE PREVENTION OF CANCER
    Mudie, Kissi
    Gebregzabher, Atsbeha
    Kassa, Desta
    INTERNATIONAL JOURNAL OF PHARMACEUTICAL SCIENCES AND RESEARCH, 2015, 6 (11): : 4556 - 4569
  • [34] Antioxidants Meet Molecular Targets for Cancer Prevention and Therapeutics
    Ahmad, Nihal
    Mukhtar, Hasan
    ANTIOXIDANTS & REDOX SIGNALING, 2013, 19 (02) : 85 - 88
  • [35] Dietary antioxidants in cancer prevention: Future directions for research
    Lindsay, DG
    DIETARY ANTICARCINOGENS AND ANTIMUTAGENS, 2000, (255): : 215 - 224
  • [36] Nutrient antioxidants in the pathogenesis and prevention of cervical dysplasias and cancer
    Romney, SL
    Palan, PR
    Basu, J
    Mikhail, M
    JOURNAL OF CELLULAR BIOCHEMISTRY, 1995, : 96 - 103
  • [37] On the Occasion of World Cancer Day 2015; the Possibility of Cancer Prevention or Treatment with Antioxidants: The Ongoing Cancer Prevention Researches
    Rafieian-Kopaie, Mahmoud
    Nasri, Hamid
    INTERNATIONAL JOURNAL OF PREVENTIVE MEDICINE, 2015, 6
  • [38] POTENTIAL ROLE OF ANTIOXIDANTS IN THE PRIMARY AND SECONDARY PREVENTION OF ATHEROSCLEROSIS IN THE ELDERLY
    LAVIE, CJ
    OKEEFE, JH
    MEHRA, MR
    MILANI, RV
    CARDIOLOGY IN THE ELDERLY, 1995, 3 (01): : 21 - 25
  • [39] THE ROLE OF ANTIOXIDANTS IN THE PREVENTION OF LOW-DENSITY LIPOPROTEIN OXIDATION
    ESTERBAUER, H
    QUEHENBERGER, O
    PUHL, H
    STRIEGL, G
    JURGENS, G
    BIOLOGICAL CHEMISTRY HOPPE-SEYLER, 1988, 369 (09): : 813 - 813
  • [40] Role of dietary antioxidants in the prevention of in vivo oxidative DNA damage
    Cooke, MS
    Evans, MD
    Mistry, N
    Lunec, J
    NUTRITION RESEARCH REVIEWS, 2002, 15 (01) : 19 - 41