INCREASED ERYTHROCYTE MAGNESIUM IN NEVER TREATED ESSENTIAL-HYPERTENSION

被引:10
|
作者
KJELDSEN, SE
SEJERSTED, OM
FREDERICHSEN, P
LEREN, P
EIDE, IK
机构
[1] Clinical Chemistry, National Institute of Occupational Health Oslo
[2] Ullevaal University Hospital, Department of Physiology, National Institute of Occupational Health, Oslo
关键词
Blood pressure; Erythrocyte; Magnesium; Potassium; Sodium;
D O I
10.1093/ajh/3.7.573
中图分类号
R6 [外科学];
学科分类号
1002 ; 100210 ;
摘要
In the present study we aimed at evaluating the intracellular concentrations of magnesium, potassium and sodium in 50-year-old, otherwise healthy white men with never treated, essential hypertension (n = 12) and in normotensive control subjects (n = 12) matched for age, sex, race, height, weight and smoking habits. Intraerythrocyte magnesium was significantly increased in the hypertensive group (P <.001) and correlated positively and significantly to blood pressure in the total group (P <.01). The intracellular potassium to sodium ratio tended to be lower in the hypertensive group (P <.05). Thus, the present study supports increased intracellular magnesium probably unrelated to intracellular potassium-sodium imbalance in never treated, essential hypertension. © 1990 by the American Journal of Hypertension, Ltd.
引用
收藏
页码:573 / 575
页数:3
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