COMPARISON OF VIRULENCE OF MYCOBACTERIUM-AVIUM COMPLEX (MAC) STRAINS ISOLATED FROM AIDS AND NON-AIDS PATIENTS

被引：17

作者：

REDDY, VM

PARIKH, K

LUNAHERRERA, J

FALKINHAM, JO

BROWN, S

GANGADHARAM, PRJ

机构：

[1] UNIV ILLINOIS,COLL MED,MYCOBACTERIOL RES LAB,CHICAGO,IL 60612

[2] VIRGINIA POLYTECH INST & STATE UNIV,BLACKSBURG,VA 24061

[3] BRONX VA HOSP,NEW YORK,NY

[4] MEM SLOAN KETTERING CANC CTR,NEW YORK,NY 10021

来源：

MICROBIAL PATHOGENESIS | 1994年 / 16卷 / 02期

关键词：

MYCOBACTERIUM AVIUM COMPLEX (MAC); VIRULENCE; MULTIPLE ISOLATES; AIDS AND NON-AIDS PATIENTS; COLONY MORPHOLOGY;

D O I：

10.1006/mpat.1994.1013

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Mycobacterium avium complex (MAC) strains from AIDS and non-AIDS patients and from the environment were studied for their colony morphology and virulence in beige mice. The majority of the MAC isolates from AIDS patients, in contrast to those from non-AIDS patients and the environment, showed increased virulence. Similarly, the majority of the MAC isolates from AIDS patients formed smooth transparent (ST) colonies, whereas most of the non-AIDS isolates formed smooth opaque (SO) or intermediate (IM) type of colonies. MAC isolates from the same AIDS patient obtained at different times were found to be heterogenic with respect to serotype, RFLP and glycolipid patterns, suggesting that these patients might be infected with more than one strain of MAC. © 1994 Academic Press. All rights reserved.

引用

页码：121 / 130

页数：10

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