INSIGHTS INTO THE ACTIVE-SITE OF THE CYTOCHROME-P-450 HEMOPROTEIN FAMILY - A UNIFYING CONCEPT BASED ON STRUCTURAL CONSIDERATIONS

被引：40
|
作者：
DUS, KM
机构：
来源：
XENOBIOTICA | 1982年 / 12卷 / 11期
关键词：
D O I：
10.3109/00498258209038948
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
引用
收藏
页码：745 / 772
页数：28
相关论文
共 50 条
  • [41] MUTAGENESIS STUDY AT A POSTULATED HYDROPHOBIC REGION NEAR THE ACTIVE-SITE OF AROMATASE CYTOCHROME-P450
    ZHOU, DJ
    CAM, LL
    LAUGHTON, CA
    KORZEKWA, KR
    CHEN, S
    JOURNAL OF BIOLOGICAL CHEMISTRY, 1994, 269 (30) : 19501 - 19508
  • [42] HYDRATION OF THE ACTIVE-SITE OF CYTOCHROME-P450CAM STUDIED BY MOLECULAR-DYNAMICS SIMULATIONS
    HELMS, VH
    WADE, RC
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1994, 208 : 82 - COMP
  • [43] Enantioselective Enzyme-Catalyzed Aziridination Enabled by Active-Site Evolution of a Cytochrome P450
    Farwell, Christopher C.
    Zhang, Ruijie K.
    McIntosh, John A.
    Hyster, Todd K.
    Arnold, Frances H.
    ACS CENTRAL SCIENCE, 2015, 1 (02) : 89 - 93
  • [44] Active-Site Hydration and Water Diffusion in Cytochrome P450cam: A Highly Dynamic Process
    Miao, Yinglong
    Baudry, Jerome
    BIOPHYSICAL JOURNAL, 2011, 101 (06) : 1493 - 1503
  • [45] TYROSINE-96 AS A NATURAL SPECTROSCOPIC PROBE OF THE CYTOCHROME-P-450CAM ACTIVE-SITE
    ATKINS, WM
    SLIGAR, SG
    BIOCHEMISTRY, 1990, 29 (05) : 1271 - 1275
  • [46] INTERACTION OF A SPIN-LABELED CHOLESTEROL DERIVATIVE WITH THE CYTOCHROME P-450SCC ACTIVE-SITE
    LANGE, R
    MAURIN, L
    LARROQUE, C
    BIENVENUE, A
    EUROPEAN JOURNAL OF BIOCHEMISTRY, 1988, 172 (01): : 189 - 195
  • [47] ELECTROMAGNETIC PROPERTIES OF ACTIVE-SITE MODEL HIGH-SPIN FERRIC CYTOCHROME-P450
    LOEW, GH
    ROHMER, MM
    BULLETIN OF THE AMERICAN PHYSICAL SOCIETY, 1979, 24 (03): : 345 - 345
  • [48] ACTIVE-SITE MODELS OF HORSERADISH-PEROXIDASE COMPOUND I AND A CYTOCHROME-P-450 ANALOG - ELECTRONIC-STRUCTURE AND ELECTRIC-FIELD GRADIENTS
    LOEW, GH
    KERT, CJ
    HJELMELAND, LM
    KIRCHNER, RF
    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1977, 99 (10) : 3534 - 3536
  • [49] NATURE AND REACTIVITY TOWARDS SUBSTRATES OF THE ACTIVE OXYGEN HEMOPROTEIN COMPLEXES INVOLVED IN THE REACTION OF PEROXIDASES AND CYTOCHROME-P-450 WITH 2-ELECTRON OXIDANTS
    MANSUY, D
    CHOTTARD, JC
    LANGE, M
    BATTIONI, JP
    JOURNAL OF MOLECULAR CATALYSIS, 1980, 7 (02): : 215 - 226
  • [50] ASYMMETRIC EPOXIDATION OF OLEFINS CATALYZED BY MANGANESE COMPLEXES OF CHIRAL STRAPPED PORPHYRINS WITH DIASTEREOTOPIC FACES - A NOVEL STRATEGY FOR STEREOCHEMICAL MODELING OF THE ACTIVE-SITE OF CYTOCHROME-P-450
    KONISHI, K
    ODA, K
    NISHIDA, K
    AIDA, T
    INOUE, S
    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1992, 114 (04) : 1313 - 1317
12345