The interdependence of water quality parameters with distance from polluting sources and depth of twenty four native wells in Abeokuta, Nigeria is examined in this study. In gross features, the bacteriological quality as monitored by coliform counts showed significant negative correlation of 0.74 and 0.60 with distance from polluting source and depth of well respectively. Most of the wells examined had construction defects and there was evidence of faecal contamination. The results highlight possible environmental impacts of lapses in construction and obvious contamination of this popular water systems. The study probably highlights the much needed awareness on the part of local residents and environmental health authorities to curb dangers inherent in poor sanitation and consumption of contaminated groundwater. The results could serve as a basis for planning and policy formulation on environmental sanitation, drainage systems, native well siting, construction, finishing and maintenance.