CUSHINGS-DISEASE IN CHILDHOOD - SURGICAL-TREATMENT

The authors present three children with Cushing's disease who underwent operation by a transsphenoidal approach, All the three patients were studied both endocrinologically and radiologically with X-ray, computerised tomography or magnetic resonance, The surgical findings were positive in two patients, in whom a pituitary adenoma was found, and negative in one case, Follow-up after operation is nine Sears for the two patients with adenoma and five years for the patient without apparent pathology, In all the three patients a favourable clinical and endocrinological result has been obtained, The authors favour transsphenoidal exploration of the pituitary gland in patients diagnosed of Cushing's disease.