COATED HYDROPHILIC POLYSTYRENE-BASED PACKING MATERIALS

被引：38

作者：

YANG, YB ^{[1
]}

REGNIER, FE ^{[1
]}

机构：

[1] PURDUE UNIV,DEPT BIOCHEM,W LAFAYETTE,IN 47907

来源：

JOURNAL OF CHROMATOGRAPHY | 1991年 / 544卷 / 1-2期

关键词：

D O I：

10.1016/S0021-9673(01)83988-1

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

A very hydrophilic high-performance liquid chromatographic base support was created from microparticulate, macroporous poly(styrene-divinylbenzene) beads. An organic monomer containing cross-linking functionalities was coated on the poly(styrene-divinylbenzene), followed by a catalyzed cross-linking reaction. The coatings formed contain only stable chemical bonds (e.g., C-C, C-O-C), and easily-derivatized hydroxyl moieties. This coated base support was evaluated for hydrophilicity, chemical stability, solvent compatibility, rigidity, and irreversible adsorption. Derivatives of the coated base support were made and applied in various modes of chromatography.

引用

页码：233 / 247

页数：15

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