GENETIC-MARKERS IN ALCOHOLIC LIVER-CIRRHOSIS

被引：2
|
作者：
LAREU, MV
ALVAREZPRECHOUS, A
PARDINAS, C
CONCHEIRO, L
CARRACEDO, A
机构：
[1] UNIV SANTIAGO DE COMPOSTELA,FAC MED,DEPT LEGAL MED,E-15705 SANTIAGO,SPAIN
[2] UNIV SANTIAGO DE COMPOSTELA,INST LEGAL MED,E-15705 SANTIAGO,SPAIN
来源：
HUMAN HEREDITY | 1992年 / 42卷 / 04期
关键词：
GENETIC MARKERS; ALCOHOLIC CIRRHOSIS; ALPHA-1-ANTITRYPSIN; HAPTOGLOBIN; ACID PHOSPHATASE;
D O I：
10.1159/000154076
中图分类号：
Q3 [遗传学];
学科分类号：
071007 ; 090102 ;
摘要：
11 genetic markers were typed in 157 individuals suffering from alcoholic cirrhosis, and compared with a random sample of healthy individuals. No significant differences were found for transferrin, specific group component, orosomucoid, esterase D, phosphogluconate dehydrogenase and adenylate kinase. Strong associations between alcoholic cirrhosis and alpha-1-antitrypsin PI*Z allele, haptoglobin HP*1 allele and acid phosphatase ACP AC phenotype were observed. The biological significance of these associations and their relationships with the development of alcoholic cirrhosis are also discussed.
引用
收藏
页码：235 / 241
页数：7
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