Screening of women at high familial risk of breast cancer

被引:1
|
作者
Narod, Steven A. [1 ,2 ]
机构
[1] Univ Toronto, Womens Coll Res Inst, 790 Bay St, Toronto, ON M5G IN8, Canada
[2] Univ Toronto, Dalla Lana Sch Publ Hlth, Toronto, ON M5G IN8, Canada
关键词
BRCA1; breast cancer; DCIS; mammography; MRI; screening;
D O I
10.2217/WHE.10.35
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Evaluation of: Kuhl C, Weigel S, Schrading S et al.: Prospective multicenter cohort study to refine management recommendations for women at elevated familial risk of breast cancer: the EVA trial. J. Clin. Oncol. 28, 1450-1457 (2010). In the EVA trial, Kuhl et al. screened 687 women at high risk of breast cancer for up to 3 years with annual MRI. A total of 27 breast cancers were diagnosed, including 11 DCIS and two local recurrences. There were no interval cancers. This data suggests that MRI screening can be used to downstage breast cancers, but larger studies with longer follow-up periods are required to confirm these findings.
引用
收藏
页码:509 / 510
页数:2
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