GENOMIC ORGANIZATION OF THE GENE AND A RELATED PSEUDOGENE FOR A HUMAN FOLATE BINDING-PROTEIN

被引：22
|
作者：
SADASIVAN, E
CEDENO, M
ROTHENBERG, SP
机构：
[1] SUNY HLTH SCI CTR,DEPT MED,DIV HEMATOL ONCOL,800 POLY PL,BROOKLYN,NY 11209
[2] DEPT VET AFFAIRS MED CTR,BROOKLYN,NY 11209
来源：
BIOCHIMICA ET BIOPHYSICA ACTA | 1992年 / 1131卷 / 01期
关键词：
FOLATE BINDING PROTEIN; GENE; PSEUDOGENE; FOLATE;
D O I：
10.1016/0167-4781(92)90103-7
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
An unprocessed pseudogene which is 90% homologous with the cDNA encoding a folate binding protein in KB cells has been cloned from a human genomic library. This pseudogene contains TGA stop codons, base deletions and substitutions and lacks a 5' region. The size of the exons and the intron-exon sites are almost identical to the organization of the gene encoding this protein which has now been characterized from genomic DNA using the polymerase chain reaction with selected primers to the cDNA.
引用
收藏
页码：91 / 94
页数：4
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