Pediatric Cardiopulmonary Bypass: Does Perfusion Mode Matter?

被引:5
|
作者
Talor, Jonathan J. [1 ,2 ]
Undar, Akif [1 ,2 ]
机构
[1] Penn State Childrens Hosp, Penn State Coll Med, Penn State Milton S Hershey Med Ctr, Hershey, PA 17033 USA
[2] Penn State Childrens Hosp, Penn State Coll Med, Penn State Hershey Pediat Cardiovasc Res Ctr, Hershey, PA 17033 USA
关键词
cardiopulmonary bypass (CPB); neonate; pediatric; perfusion;
D O I
10.1177/2150135110394218
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
This current review describes how components of the cardiopulmonary bypass (CPB) circuit are selected and examines the benefits of pulsatile perfusion for use during CPB. Pulsatile flow generates significantly greater surplus hemodynamic energy (SHE) than nonpulsatile flow; higher SHE values have been associated with better microcirculation perfusion, lower rates of systemic inflammatory response, and better vital organ protection. Pulsatile perfusion may have a positive effect on clinical outcomes, play a role in preserving homeostasis, and help to decrease morbidity associated with CPB.
引用
收藏
页码:296 / 300
页数:5
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